Land: Malaysia
Språk: engelska
Källa: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
PSEUDOEPHEDRINE HYDROCHLORIDE; TRIPROLIDINE HYDROCHLORIDE
PAHANG PHARMACY SDN. BHD.
PSEUDOEPHEDRINE HYDROCHLORIDE; TRIPROLIDINE HYDROCHLORIDE
10tablet Tablets; 20tablet Tablets; 30tablet Tablets; 50tablet Tablets; 100tablet Tablets; 250tablet Tablets; 500tablet Tablets; 1000tablet Tablets
Noripharma Sdn. Bhd.
CORIFED TABLET _CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ TRIPROLIDINE HYDROCHLORIDE 2.5MG/PSEUDOEPHEDRINE HYDROCHLORIDE 60MG IN THIS LEAFLET : 1. What is CORIFED used for 2. How does CORIFED works 3. Before you take CORIFED 4. How to take CORIFED 5. While using CORIFED 6. Side effects 7. How to store and dispose CORIFED 8. Product description 9. Manufacturer 10. Date of Revision 1. WHAT IS CORIFED USE FOR This medicine is used to relieve the symptoms of colds, flu and allergies including runny nose, watery eyes, nasal congestion and blocked sinuses. 2. HOW CORIFED WORKS The tablets contain pseudoephedrine hydrochloride which is a decongestant that shrinks swollen nasal mucous membrane, reduces nasal hyperemia, relieves nasal, edema and sinus congestion and increase nasal airway potency. Triprolidine hydrochloride is an antihistamine that that reduces the natural chemical histamine in the body and helps to stop sneezy, runny nose and watery eyes. It also has anticholinergic actions and provide a drying effect on the nasal mucosa. 3. BEFORE YOU TAKE CORIFED _When you must not take it_ • If you have very high blood pressure or severe heart disease. • If you have ever had a bad reaction to any of the ingredients. • If you are taking, or have taken in the last two weeks, drugs for depression known as Monoamine Oxidase Inhibitor (MAOIs) such as isocarboxazid, phenelzine rasagiline, selegiline or tranylcypromine _ _ _Before you start to take it._ Inform your doctor if you have • liver or kidney problems. • high blood pressure or heart disease. • diabetes or if you been told by your doctor that you have an intolerance to some sugars. • an overactive thyroid gland. • glaucoma (increased pressure in the eye). • prostate problems (difficulty with passing water or needing to pass water often). • taking alcohol. • pregnant or plan to become pregnant during treatment • breast-feeding a baby. _ _ _Taking other medicines _ Please tell your doctor or pharmacist if you are taking or have recently ta Läs hela dokumentet
1 CORIFED TABLET COMPOSITION: Each tablet contains: Triprolidine Hydrochloride 2.5mg Pseudoephedrine Hydrochloride 60mg DESCRIPTION: A yellow round shaped tablet with score line on one side. PHARMACODYNAMICS: Pseudoephedrine is an orally effective upper respiratory tract decongestant. It acts on alpha- adrenergic receptors in the mucosa of the respiratory tract, producing vasoconstriction. It shrinks swollen nasal mucous membrane; reduces tissue hyperemia, edema and nasal congestion; and increases nasal airway potency. Drainage of sinus secretions may be increased and obstructed eustachian ostia may be opened. Triprolidine is an antihistamine (H1-receptor). It acts by competing with histamine for H1- receptor sites on effector cells. It prevents, but does not reverse, responses mediated by histamine alone. It also has anticholinergic actions and provides a drying effect on the nasal mucosa. PHARMACOKINETICS: Pseudoephedrine is almost completely and rapidly absorbed from the G.I.T. Pseudoephedrine is incompletely metabolised in the liver. Onset of action is within 15 to 30 minutes and has a duration of action for 3 to 4 hours. Elimination is renal and about 75% is excreted unchanged. The rate of excretion is accelerated in acidic urine. Triprolidine is absorbed from the G.I.T. The time to peak effect is 2 to 3 hours, half life of 3 to 3.3 hours and a duration of action of 4 to 8 hours. It is metabolised in the liver and is excreted in the urine. INDICATION: Corifed Tablet is indicated for the temporary relief of nasal and sinus congestion, sneezing and rhinorrhea associated with the common cold and allergic rhinitis. ROUTE OF ADMINISTRATION: Oral administration. RECOMMENDED DOSE: Adults and children over 12 years : 1 tablet three times a day. Children 6 – 12 years : ½ tablet three times a day. CONTRAINDICATION: Contraindicated in patients with a known hypersensitivity to pseudoephedrine or triprolidine. Also contraindicated in patients under treatment with monoamine oxidase inhibitors or within two weeks of sto Läs hela dokumentet