Bob Martin Flea Killing Mousse Plus for Cats and Kittens

Kraj: Wielka Brytania

Język: angielski

Źródło: VMD (Veterinary Medicines Directorate)

Składnik aktywny:

Piperonyl Butoxide, Pyrethrins

Dostępny od:

Bob Martin (UK) Ltd

INN (International Nazwa):

Piperonyl Butoxide, Pyrethrins

Forma farmaceutyczna:

Cutaneous foam

Typ recepty:

AVM-GSL - Authorised Veterinary Medicine – General Sales List

Grupa terapeutyczna:

Cats

Dziedzina terapeutyczna:

Ectoparasiticide

Status autoryzacji:

Expired

Data autoryzacji:

1996-04-16

Charakterystyka produktu

!mss19072001 MS/07/95
Page 1 of 4
REFERENCE NO:
MS/07/95
REVISION NO:
Six
REASON FOR REVISION:
MA renewal (UK)
INITIALS OF REVISER:
MSS
DATE OF ISSUE:
19/07/01
SUMMARY OF PRODUCT CHARACTERISTICS
1)
NAME OF PRODUCT:
Bob Martin Flea Killing Mousse Plus for Cats & Kittens
2)
QUALITATIVE AND QUANTITATIVE COMPOSITION:
FORMULATION:
Active Ingredients
% w/w
Pyrethrins (free)
0.05
Piperonyl Butoxide (free)
0.5
Sectrol Concentrate supplying:
Pyrethrins (encapsulated)
0.1
Piperonyl Butoxide (encapsulated)
0.8
3)
PHARMACEUTICAL FORM: Cutaneous foam
4)
PHARMACOLOGICAL PROPERTIES: The pyrethrins are potent, non-systemic,
contact insecticides causing a rapid paralysis or "knockdown", death
occurring at a later
stage. Their mechanism of action is considered to involve inhibition
of the inactivation
of sodium channels and the activation of potassium conductance at the
neurone axon
level. This results in prolonged action potentials, repetitive
neuronal firing after a
single stimulus and spontaneous trains of action potentials.
The insecticidal activity of the pyrethrins is markedly enhanced by
the inclusion of
cytochrome P
450
inhibitors which decrease their rate of metabolism by the insects;
piperonyl butoxide is a methylenedioxyphenol synergist for pyrethrins
and related
insecticides and is included in the formulation.
Pyrethrins and piperonyl butoxide are incorporated both as a free
active component for
rapid "knockdown" effect and as a microencapsulated component
providing sustained
release of active ingredients to maintain insecticidal activity for up
to 14 days.
5)
CLINICAL PARTICULARS:
5.1
Target Species:
Cats
5.2
Therapeutic Indications: The product is indicated for the control of
fleas
(_Ctenocephalides_ spp.) on cats.
5.3
Contra-indications: Do not use on nursing queens or kittens less than
twelve
weeks old. Do not use on animals with known sensitivity to pyrethrins.
!mss19072001 MS/07/95
Page 2 of 4
5.4
Undesirable Effects: Pyrethrins and piperonyl butoxide, both
individually and
in combination, possess low toxicity in