Bob Martin Flea Killing Mousse Plus for Cats and Kittens

देश: यूनाइटेड किंगडम

भाषा: अंग्रेज़ी

स्रोत: VMD (Veterinary Medicines Directorate)

सक्रिय संघटक:

Piperonyl Butoxide, Pyrethrins

थमां उपलब्ध:

Bob Martin (UK) Ltd

INN (इंटरनेशनल नाम):

Piperonyl Butoxide, Pyrethrins

फार्मास्यूटिकल फॉर्म:

Cutaneous foam

प्रिस्क्रिप्शन प्रकार:

AVM-GSL - Authorised Veterinary Medicine – General Sales List

चिकित्सीय समूह:

Cats

चिकित्सीय क्षेत्र:

Ectoparasiticide

प्राधिकरण का दर्जा:

Expired

प्राधिकरण की तारीख:

1996-04-16

उत्पाद विशेषताएं

!mss19072001 MS/07/95
Page 1 of 4
REFERENCE NO:
MS/07/95
REVISION NO:
Six
REASON FOR REVISION:
MA renewal (UK)
INITIALS OF REVISER:
MSS
DATE OF ISSUE:
19/07/01
SUMMARY OF PRODUCT CHARACTERISTICS
1)
NAME OF PRODUCT:
Bob Martin Flea Killing Mousse Plus for Cats & Kittens
2)
QUALITATIVE AND QUANTITATIVE COMPOSITION:
FORMULATION:
Active Ingredients
% w/w
Pyrethrins (free)
0.05
Piperonyl Butoxide (free)
0.5
Sectrol Concentrate supplying:
Pyrethrins (encapsulated)
0.1
Piperonyl Butoxide (encapsulated)
0.8
3)
PHARMACEUTICAL FORM: Cutaneous foam
4)
PHARMACOLOGICAL PROPERTIES: The pyrethrins are potent, non-systemic,
contact insecticides causing a rapid paralysis or "knockdown", death
occurring at a later
stage. Their mechanism of action is considered to involve inhibition
of the inactivation
of sodium channels and the activation of potassium conductance at the
neurone axon
level. This results in prolonged action potentials, repetitive
neuronal firing after a
single stimulus and spontaneous trains of action potentials.
The insecticidal activity of the pyrethrins is markedly enhanced by
the inclusion of
cytochrome P
450
inhibitors which decrease their rate of metabolism by the insects;
piperonyl butoxide is a methylenedioxyphenol synergist for pyrethrins
and related
insecticides and is included in the formulation.
Pyrethrins and piperonyl butoxide are incorporated both as a free
active component for
rapid "knockdown" effect and as a microencapsulated component
providing sustained
release of active ingredients to maintain insecticidal activity for up
to 14 days.
5)
CLINICAL PARTICULARS:
5.1
Target Species:
Cats
5.2
Therapeutic Indications: The product is indicated for the control of
fleas
(_Ctenocephalides_ spp.) on cats.
5.3
Contra-indications: Do not use on nursing queens or kittens less than
twelve
weeks old. Do not use on animals with known sensitivity to pyrethrins.
!mss19072001 MS/07/95
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5.4
Undesirable Effects: Pyrethrins and piperonyl butoxide, both
individually and
in combination, possess low toxicity in