Bob Martin Flea Killing Mousse Plus for Cats and Kittens

البلد: المملكة المتحدة

اللغة: الإنجليزية

المصدر: VMD (Veterinary Medicines Directorate)

العنصر النشط:

Piperonyl Butoxide, Pyrethrins

متاح من:

Bob Martin (UK) Ltd

INN (الاسم الدولي):

Piperonyl Butoxide, Pyrethrins

الشكل الصيدلاني:

Cutaneous foam

نوع الوصفة الطبية :

AVM-GSL - Authorised Veterinary Medicine – General Sales List

المجموعة العلاجية:

Cats

المجال العلاجي:

Ectoparasiticide

الوضع إذن:

Expired

تاريخ الترخيص:

1996-04-16

خصائص المنتج

!mss19072001 MS/07/95
Page 1 of 4
REFERENCE NO:
MS/07/95
REVISION NO:
Six
REASON FOR REVISION:
MA renewal (UK)
INITIALS OF REVISER:
MSS
DATE OF ISSUE:
19/07/01
SUMMARY OF PRODUCT CHARACTERISTICS
1)
NAME OF PRODUCT:
Bob Martin Flea Killing Mousse Plus for Cats & Kittens
2)
QUALITATIVE AND QUANTITATIVE COMPOSITION:
FORMULATION:
Active Ingredients
% w/w
Pyrethrins (free)
0.05
Piperonyl Butoxide (free)
0.5
Sectrol Concentrate supplying:
Pyrethrins (encapsulated)
0.1
Piperonyl Butoxide (encapsulated)
0.8
3)
PHARMACEUTICAL FORM: Cutaneous foam
4)
PHARMACOLOGICAL PROPERTIES: The pyrethrins are potent, non-systemic,
contact insecticides causing a rapid paralysis or "knockdown", death
occurring at a later
stage. Their mechanism of action is considered to involve inhibition
of the inactivation
of sodium channels and the activation of potassium conductance at the
neurone axon
level. This results in prolonged action potentials, repetitive
neuronal firing after a
single stimulus and spontaneous trains of action potentials.
The insecticidal activity of the pyrethrins is markedly enhanced by
the inclusion of
cytochrome P
450
inhibitors which decrease their rate of metabolism by the insects;
piperonyl butoxide is a methylenedioxyphenol synergist for pyrethrins
and related
insecticides and is included in the formulation.
Pyrethrins and piperonyl butoxide are incorporated both as a free
active component for
rapid "knockdown" effect and as a microencapsulated component
providing sustained
release of active ingredients to maintain insecticidal activity for up
to 14 days.
5)
CLINICAL PARTICULARS:
5.1
Target Species:
Cats
5.2
Therapeutic Indications: The product is indicated for the control of
fleas
(_Ctenocephalides_ spp.) on cats.
5.3
Contra-indications: Do not use on nursing queens or kittens less than
twelve
weeks old. Do not use on animals with known sensitivity to pyrethrins.
!mss19072001 MS/07/95
Page 2 of 4
5.4
Undesirable Effects: Pyrethrins and piperonyl butoxide, both
individually and
in combination, possess low toxicity in