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OXYBUTININ WINTHROP
1
OXYBUTYNIN WINTHROP
_Oxybutynin Hydrochloride_
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Oxybutynin
Winthrop.
It does not contain all the available
information.
It does not take the place of talking
to your doctor or pharmacist.
All medicines have risks and
benefits. Your doctor or pharmacist
has weighed the risks of you taking
Oxybutynin Winthrop against the
benefits they expect it will have for
you.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH THE MEDICINE.
You may need to read it again.
WHAT OXYBUTYNIN
WINTHROP IS USED FOR
Oxybutynin Winthrop is used to
decrease the urgency and the
frequency of urination. Oxybutynin
Winthrop works by relaxing the
bladder smooth muscle and helps to
decrease muscle spasm. This delays
the initial desire and the urge to
urinate.
Your doctor may have prescribed
Oxybutynin Winthrop for another
reason. Ask your doctor if you have
any questions about why Oxybutynin
Winthrop has been prescribed for
you.
There is no evidence that
Oxybutynin Winthrop is addictive.
This medicine is available only with
a doctor's prescription.
Oxybutynin Winthrop is not
recommended for use in children
under the age of 5 years, as there
have been no studies of its effects in
children.
BEFORE YOU TAKE
OXYBUTYNIN WINTHROP
_WHEN YOU MUST NOT TAKE IT_
DO NOT TAKE OXYBUTYNIN WINTHROP
IF YOU HAVE AN ALLERGY TO
OXYBUTYNIN WINTHROP OR ANY OF
THE INGREDIENTS LISTED AT THE END OF
THIS LEAFLET.
DO NOT TAKE OXYBUTYNIN WINTHROP
IF YOU HAVE:
*
Angle closure glaucoma or
shallow anterior chamber -
disorders of the eye
*
Partial or complete intestinal
blockage; stomach, intestinal or
large bowel problems including
colitis (inflammation of the
colon)
*
Myasthenia gravis - a disease of
the muscles
*
Urinary tract blockage
*
Severe bleeding
DO NOT TAKE OXYBUTYNIN WINT
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제품 특성 요약
Oxybutynin-winthrop-ccsdsv2-
piv8-d1-17jan13
Page 1
PRODUCT INFORMATION
OXYBUTYNIN WINTHROP
NAME OF THE MEDICINE
Each tablet contains oxybutynin hydrochloride 5mg.
The chemical structure of oxybutynin
hydrochloride is the following:
CAS: 1508-65-2
DESCRIPTION
Oxybutynin hydrochloride is 4-diethylamino-2-butynyl phenylcyclohexylglycolate hydrochloride.
It is a white crystalline solid (MW 393.9), which is readily soluble in water and acids, but
relatively insoluble in alkalis.
PHARMACOLOGY
Oxybutynin hydrochloride exerts a direct antispasmodic effect on smooth muscle and inhibits
the muscarinic action of acetylcholine on smooth muscle. Oxybutynin hydrochloride exhibits
four to ten times the antispasmodic potency of atropine, but only one fifth of the anticholinergic
activity of atropine on the rabbit detrusor muscle. No blocking effects occur at skeletal
neuromuscular junctions or autonomic ganglia (antinicotinic effects).
Oxybutynin Winthrop relaxes bladder smooth muscle. In patients with conditions characterised
by involuntary bladder contractions, cystometric studies have demonstrated that Oxybutynin
Winthrop increases bladder (vesical) capacity, diminishes the frequency of uninhibited
contractions of the detrusor muscle, and delays the initial desire to void. Oxybutynin Winthrop
thus decreases urgency and the frequency of both incontinent episodes and voluntary
urination.
CLASS
Antispasmodic, antocholinergic.
PHARMACOKINETICS
Oxybutynin hydrochloride is readily absorbed (peak plasma concentration in approx. 1 hour)
and rapidly eliminated (plasma half life about 2 hours). Absolute
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