Maa: Australia
Kieli: englanti
Lähde: Department of Health (Therapeutic Goods Administration)
Oxybutynin hydrochloride
Sanofi-Aventis Australia Pty Ltd
Medicine Registered
OXYBUTININ WINTHROP 1 OXYBUTYNIN WINTHROP _Oxybutynin Hydrochloride_ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Oxybutynin Winthrop. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor or pharmacist has weighed the risks of you taking Oxybutynin Winthrop against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT OXYBUTYNIN WINTHROP IS USED FOR Oxybutynin Winthrop is used to decrease the urgency and the frequency of urination. Oxybutynin Winthrop works by relaxing the bladder smooth muscle and helps to decrease muscle spasm. This delays the initial desire and the urge to urinate. Your doctor may have prescribed Oxybutynin Winthrop for another reason. Ask your doctor if you have any questions about why Oxybutynin Winthrop has been prescribed for you. There is no evidence that Oxybutynin Winthrop is addictive. This medicine is available only with a doctor's prescription. Oxybutynin Winthrop is not recommended for use in children under the age of 5 years, as there have been no studies of its effects in children. BEFORE YOU TAKE OXYBUTYNIN WINTHROP _WHEN YOU MUST NOT TAKE IT_ DO NOT TAKE OXYBUTYNIN WINTHROP IF YOU HAVE AN ALLERGY TO OXYBUTYNIN WINTHROP OR ANY OF THE INGREDIENTS LISTED AT THE END OF THIS LEAFLET. DO NOT TAKE OXYBUTYNIN WINTHROP IF YOU HAVE: * Angle closure glaucoma or shallow anterior chamber - disorders of the eye * Partial or complete intestinal blockage; stomach, intestinal or large bowel problems including colitis (inflammation of the colon) * Myasthenia gravis - a disease of the muscles * Urinary tract blockage * Severe bleeding DO NOT TAKE OXYBUTYNIN WINT Lue koko asiakirja
Oxybutynin-winthrop-ccsdsv2- piv8-d1-17jan13 Page 1 PRODUCT INFORMATION OXYBUTYNIN WINTHROP NAME OF THE MEDICINE Each tablet contains oxybutynin hydrochloride 5mg. The chemical structure of oxybutynin hydrochloride is the following: CAS: 1508-65-2 DESCRIPTION Oxybutynin hydrochloride is 4-diethylamino-2-butynyl phenylcyclohexylglycolate hydrochloride. It is a white crystalline solid (MW 393.9), which is readily soluble in water and acids, but relatively insoluble in alkalis. PHARMACOLOGY Oxybutynin hydrochloride exerts a direct antispasmodic effect on smooth muscle and inhibits the muscarinic action of acetylcholine on smooth muscle. Oxybutynin hydrochloride exhibits four to ten times the antispasmodic potency of atropine, but only one fifth of the anticholinergic activity of atropine on the rabbit detrusor muscle. No blocking effects occur at skeletal neuromuscular junctions or autonomic ganglia (antinicotinic effects). Oxybutynin Winthrop relaxes bladder smooth muscle. In patients with conditions characterised by involuntary bladder contractions, cystometric studies have demonstrated that Oxybutynin Winthrop increases bladder (vesical) capacity, diminishes the frequency of uninhibited contractions of the detrusor muscle, and delays the initial desire to void. Oxybutynin Winthrop thus decreases urgency and the frequency of both incontinent episodes and voluntary urination. CLASS Antispasmodic, antocholinergic. PHARMACOKINETICS Oxybutynin hydrochloride is readily absorbed (peak plasma concentration in approx. 1 hour) and rapidly eliminated (plasma half life about 2 hours). Absolute Lue koko asiakirja