Oxybutynin Winthrop

देश: ऑस्ट्रेलिया

भाषा: अंग्रेज़ी

स्रोत: Department of Health (Therapeutic Goods Administration)

सक्रिय संघटक:

Oxybutynin hydrochloride

थमां उपलब्ध:

Sanofi-Aventis Australia Pty Ltd

वर्ग:

Medicine Registered

सूचना पत्रक

OXYBUTININ WINTHROP
1
OXYBUTYNIN WINTHROP
_Oxybutynin Hydrochloride_
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Oxybutynin
Winthrop.
It does not contain all the available
information.
It does not take the place of talking
to your doctor or pharmacist.
All medicines have risks and
benefits. Your doctor or pharmacist
has weighed the risks of you taking
Oxybutynin Winthrop against the
benefits they expect it will have for
you.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH THE MEDICINE.
You may need to read it again.
WHAT OXYBUTYNIN
WINTHROP IS USED FOR
Oxybutynin Winthrop is used to
decrease the urgency and the
frequency of urination. Oxybutynin
Winthrop works by relaxing the
bladder smooth muscle and helps to
decrease muscle spasm. This delays
the initial desire and the urge to
urinate.
Your doctor may have prescribed
Oxybutynin Winthrop for another
reason. Ask your doctor if you have
any questions about why Oxybutynin
Winthrop has been prescribed for
you.
There is no evidence that
Oxybutynin Winthrop is addictive.
This medicine is available only with
a doctor's prescription.
Oxybutynin Winthrop is not
recommended for use in children
under the age of 5 years, as there
have been no studies of its effects in
children.
BEFORE YOU TAKE
OXYBUTYNIN WINTHROP
_WHEN YOU MUST NOT TAKE IT_
DO NOT TAKE OXYBUTYNIN WINTHROP
IF YOU HAVE AN ALLERGY TO
OXYBUTYNIN WINTHROP OR ANY OF
THE INGREDIENTS LISTED AT THE END OF
THIS LEAFLET.
DO NOT TAKE OXYBUTYNIN WINTHROP
IF YOU HAVE:
*
Angle closure glaucoma or
shallow anterior chamber -
disorders of the eye
*
Partial or complete intestinal
blockage; stomach, intestinal or
large bowel problems including
colitis (inflammation of the
colon)
*
Myasthenia gravis - a disease of
the muscles
*
Urinary tract blockage
*
Severe bleeding
DO NOT TAKE OXYBUTYNIN WINT

उत्पाद विशेषताएं

Oxybutynin-winthrop-ccsdsv2-
piv8-d1-17jan13 

Page 1  

PRODUCT INFORMATION 
OXYBUTYNIN WINTHROP 
NAME OF THE MEDICINE 
Each tablet contains oxybutynin hydrochloride 5mg. 

The chemical structure of oxybutynin
hydrochloride is the following: 

CAS: 1508-65-2 
DESCRIPTION 
Oxybutynin hydrochloride is 4-diethylamino-2-butynyl phenylcyclohexylglycolate hydrochloride.  
It  is  a  white  crystalline  solid  (MW  393.9),  which  is  readily  soluble  in  water  and  acids,  but 
relatively insoluble in alkalis. 
PHARMACOLOGY 
Oxybutynin hydrochloride exerts a direct antispasmodic effect on  smooth muscle and inhibits 
the  muscarinic  action  of  acetylcholine  on  smooth  muscle.    Oxybutynin  hydrochloride  exhibits 
four to ten times the antispasmodic potency of atropine, but only one fifth of the anticholinergic 
activity  of  atropine  on  the  rabbit  detrusor  muscle.    No  blocking  effects  occur  at  skeletal 
neuromuscular junctions or autonomic ganglia (antinicotinic effects). 
Oxybutynin Winthrop relaxes bladder smooth muscle.  In patients with conditions characterised 
by  involuntary  bladder  contractions,  cystometric  studies  have  demonstrated  that  Oxybutynin 
Winthrop  increases  bladder  (vesical)  capacity,  diminishes  the  frequency  of  uninhibited 
contractions of the detrusor muscle, and delays the initial desire to void.  Oxybutynin Winthrop 
thus  decreases  urgency  and  the  frequency  of  both  incontinent  episodes  and  voluntary 
urination. 
CLASS 
Antispasmodic, antocholinergic. 
PHARMACOKINETICS 
Oxybutynin  hydrochloride  is  readily  absorbed  (peak  plasma  concentration  in  approx.  1  hour) 
and  rapidly  eliminated  (plasma  half  life  about  2  hours).    Absolute