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HEPARINISED SALINE INJECTION
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HEPARINISED SALINE
INJECTION
_ _
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Heparinised Saline
Injection. It does not contain all the
available information. It does not
take the place of talking to your
doctor or pharmacist.
All medicines have benefits and
risks. Your doctor has weighed the
risks of you being given Heparinised
Saline Injection against the benefits
this medicine is expected to have for
you.
This medicine is likely to be used
while you are at the clinic or in
hospital. If possible, please read this
leaflet carefully before this medicine
is given to you. In some cases this
leaflet may be given to you after the
medicine has been used.
IF YOU HAVE ANY CONCERNS ABOUT
BEING GIVEN THIS MEDICINE, ASK YOUR
DOCTOR, NURSE OR PHARMACIST.
KEEP THIS LEAFLET.
You may need to read it again.
This medicine is available only with
a doctor's prescription.
WHAT HEPARINISED
SALINE INJECTION IS
USED FOR
Heparinised Saline Injection belongs
to a group of medicines known as
anticoagulants. Anticoagulants work
by decreasing the clotting ability of
your blood and help stop clots
forming in the blood vessels.
Anticoagulants are sometimes called
"blood thinners", although they do
not actually thin the blood. Heparin
will not dissolve blood clots that
have already formed, but it may
prevent any clots that have already
formed from becoming larger and
causing serious problems.
Heparinised Saline Injection is used
to prevent the blocking of injection
equipment often caused by blood
clots.
Heparinised Saline Injection may be
used for the treatment of other
conditions that are not mentioned
above. Your doctor will b
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製品の特徴
Version: pfphepsi11012
Supersedes: pfphepsi11210
Page 1 of 7
PRODUCT INFORMATION
HEPARINISED SALINE INJECTION (PORCINE MUCOUS)
NAME OF THE MEDICINE
Heparin sodium BP
Heparin is a heterogeneous group of straight-chain anionic mucopolysaccharides, called
glycosaminoglycans, possessing anticoagulant properties. It is composed of polymers of
alternating derivations of α-D-glucosamido (_N_-sulfated _O_-sulfated or _N_-acetylated) and _O_-
sulfated uronic acid (α-L-iduronic acid or β-D-glucuronic acid).
HEPARIN CAS REGISTRY NUMBER IS 9005-49-6.
DESCRIPTION
Heparin sodium is a preparation containing the sodium salt of a sulphated
glucosaminoglycan
present in mammalian tissues. It is prepared from the intestinal mucosae of pigs. Heparin
sodium is a white or almost white powder, moderately hygroscopic,
freely soluble in water.
Heparinised Saline Injection is a clear, colourless, sterile, preservative-free solution
containing Heparin Sodium BP (porcine mucous) and Sodium Chloride BP in Water for
Injections BP.
PHARMACOLOGY
CLASS OF DRUG: ANTICOAGULANT
MECHANISM OF ACTION:
Heparin is a naturally occurring mucopolysaccharide with _in vitro_ and _in vivo_ anticoagulant
activity. Heparin acts at multiple sites in the normal coagulation systems. Small amounts of
heparin in combination with antithrombin III (heparin cofactor) can inhibit thrombosis by
inactivating activated factor X and inhibiting the conversion of prothrombin to thrombin.
Once active thrombosis has developed, larger amounts of heparin can inhibit further
coagulation by inactivating thrombin, which in turn prevents the conversion of fibrino
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