NOREPINEPHRINE BITARTRATE IN 5% DEXTROSE INJECTION SOLUTION

Country: কানাডা

ভাষা: ইংরেজি

সূত্র: Health Canada

সক্রিয় উপাদান:

NOREPINEPHRINE (NOREPINEPHRINE BITARTRATE)

থেকে পাওয়া:

BAXTER CORPORATION

এটিসি কোড:

C01CA03

INN (International Name):

NOREPINEPHRINE

ডোজ:

0.032MG

ফার্মাসিউটিকাল ফর্ম:

SOLUTION

রচনা:

NOREPINEPHRINE (NOREPINEPHRINE BITARTRATE) 0.032MG

প্রশাসন রুট:

INTRAVENOUS

প্যাকেজ ইউনিট:

15G/50G

প্রেসক্রিপশন টাইপ:

Ethical

Therapeutic area:

ALPHA-AND BETA-ADRENERGIC AGONISTS

পণ্য সারাংশ:

Active ingredient group (AIG) number: 0131301003; AHFS:

অনুমোদন অবস্থা:

APPROVED

অনুমোদন তারিখ:

2020-07-02

পণ্য বৈশিষ্ট্য

_Prescribing Information - Norepinephrine Bitartrate in 5% Dextrose
Injection _
_USP)_
_Page 1 of 13 _
PRESCRIBING INFORMATION
NOREPINEPHRINE BITARTRATE IN 5% DEXTROSE INJECTION
0.016 mg / mL and 0.032 mg / mL norepinephrine
(as norepinephrine
bitartrate)
Sterile Solution
for Intravenous Infusion
Manufacturer Standard
SYMPATHOMIMETIC AMINE FOR USE IN HYPOTENSIVE EMERGENCIES
Baxter Corporation
Date of Revision:
June 24, 2021
Mississauga, Ontario
L5N 0C2
Control No.: 249005
Baxter and VIAFLO are Trademarks of Baxter International Inc.
_Prescribing Information - Norepinephrine Bitartrate in 5% Dextrose
Injection _
_USP)_
_Page 2 of 13 _
DESCRIPTION
Norepinephrine
(sometimes
referred to as _ l-arterenol/Levarterenol or l-norepinephrine) _is a
sympathomimetic
amine which differs from epinephrine by the absence of a methyl group
on the
nitrogen atom.
ACTIONS
Norepinephrine bitartrate functions
as a powerful
peripheral
vasoconstrictor
(alpha-adrenergic
action) and as a potent inotropic
stimulator
of the heart and dilator of coronary
arteries (beta-
adrenergic action). Both of these actions result in an increase in
systemic blood
pressure and
coronary artery blood flow. Cardiac output will vary reflexly in
response to
systemic hypertension
but is usually
increased in hypotensive
man when the blood
pressure is
raised
to an optimal
level.
In myocardial
infarction
accompanied
by
hypotension.
Norepinephrine bitartrate usually
increases aortic blood pressure, coronary artery blood flow, and
myocardial oxygenation,
thereby
helping to limit the area of myocardial ischemia and infarction.
Venous return is
increased and the
heart tends to resume a more normal rate and rhythm than in the
hypotensive
state.
In hypotension
that persists after correction of blood
volume
deficits,
norepinephrine bitartrate
helps raise the
blood pressure to an optimal level and establish a more adequate
circulation.
In _myocardial infarction, _norepinephrine bitartrate has been shown
to increase greatly the patient
survival rate.
Norepinephrine bitartr