NOREPINEPHRINE BITARTRATE IN 5% DEXTROSE INJECTION SOLUTION

Страна: Канада

Език: английски

Източник: Health Canada

Активна съставка:

NOREPINEPHRINE (NOREPINEPHRINE BITARTRATE)

Предлага се от:

BAXTER CORPORATION

АТС код:

C01CA03

INN (Международно Name):

NOREPINEPHRINE

дозиране:

0.032MG

Лекарствена форма:

SOLUTION

Композиция:

NOREPINEPHRINE (NOREPINEPHRINE BITARTRATE) 0.032MG

Начин на приложение:

INTRAVENOUS

Броя в опаковка:

15G/50G

Вид предписание :

Ethical

Терапевтична област:

ALPHA-AND BETA-ADRENERGIC AGONISTS

Каталог на резюме:

Active ingredient group (AIG) number: 0131301003; AHFS:

Статус Оторизация:

APPROVED

Дата Оторизация:

2020-07-02

Данни за продукта

_Prescribing Information - Norepinephrine Bitartrate in 5% Dextrose
Injection _
_USP)_
_Page 1 of 13 _
PRESCRIBING INFORMATION
NOREPINEPHRINE BITARTRATE IN 5% DEXTROSE INJECTION
0.016 mg / mL and 0.032 mg / mL norepinephrine
(as norepinephrine
bitartrate)
Sterile Solution
for Intravenous Infusion
Manufacturer Standard
SYMPATHOMIMETIC AMINE FOR USE IN HYPOTENSIVE EMERGENCIES
Baxter Corporation
Date of Revision:
June 24, 2021
Mississauga, Ontario
L5N 0C2
Control No.: 249005
Baxter and VIAFLO are Trademarks of Baxter International Inc.
_Prescribing Information - Norepinephrine Bitartrate in 5% Dextrose
Injection _
_USP)_
_Page 2 of 13 _
DESCRIPTION
Norepinephrine
(sometimes
referred to as _ l-arterenol/Levarterenol or l-norepinephrine) _is a
sympathomimetic
amine which differs from epinephrine by the absence of a methyl group
on the
nitrogen atom.
ACTIONS
Norepinephrine bitartrate functions
as a powerful
peripheral
vasoconstrictor
(alpha-adrenergic
action) and as a potent inotropic
stimulator
of the heart and dilator of coronary
arteries (beta-
adrenergic action). Both of these actions result in an increase in
systemic blood
pressure and
coronary artery blood flow. Cardiac output will vary reflexly in
response to
systemic hypertension
but is usually
increased in hypotensive
man when the blood
pressure is
raised
to an optimal
level.
In myocardial
infarction
accompanied
by
hypotension.
Norepinephrine bitartrate usually
increases aortic blood pressure, coronary artery blood flow, and
myocardial oxygenation,
thereby
helping to limit the area of myocardial ischemia and infarction.
Venous return is
increased and the
heart tends to resume a more normal rate and rhythm than in the
hypotensive
state.
In hypotension
that persists after correction of blood
volume
deficits,
norepinephrine bitartrate
helps raise the
blood pressure to an optimal level and establish a more adequate
circulation.
In _myocardial infarction, _norepinephrine bitartrate has been shown
to increase greatly the patient
survival rate.
Norepinephrine bitartr