SEVOFLURANE inhalant

国家: 美国

语言: 英文

来源: NLM (National Library of Medicine)

有效成分:

SEVOFLURANE (UNII: 38LVP0K73A) (SEVOFLURANE - UNII:38LVP0K73A)

可用日期:

MWI

INN（国际名称）:

SEVOFLURANE

组成:

SEVOFLURANE 1 mL in 1 mL

给药途径:

RESPIRATORY (INHALATION)

处方类型:

PRESCRIPTION

疗效迹象:

Sevoflurane is indicated for induction and maintenance of general anesthesia in dogs. Sevoflurane is contraindicated in dogs with a known sensitivity to sevoflurane or other halogenated agents.

產品總結:

Sevoflurane is packaged in amber colored bottles containing 250 mL sevoflurane, V1 510090.

授权状态:

New Animal Drug Application

产品特点

SEVOFLURANE- SEVOFLURANE INHALANT
MWI
----------
SEVOFLURANE
SEVOFLURANE
INHALATION ANESTHETIC FOR USE IN DOGS
CAUTION: FEDERAL LAW RESTRICTS THIS DRUG TO USE BY OR ON THE ORDER OF
A
LICENSED VETERINARIAN.
DESCRIPTION:
Sevoflurane, a volatile liquid, is a halogenated general inhalation
anesthetic drug. Its
chemical name is fluoromethyl 2,2,2-trifluoro-l-(trifluoromethyl)
ethyl ether, and its
structural formula is:
Sevoflurane Physical Constants are:
Molecular Weight
200.05
Boiling Point at 760 mm Hg
58.6 °C
Specific Gravity at 20°C
1.520 -
1.525 g/mL
Vapor Pressure in mm Hg
at 20
°C
157
at 25
°C
197
at 36
°C
317
Distribution Partition Coefficients
at 37
°C:
Blood/Gas
0.63 - 0.69
Water/Gas
0.36
Olive Oil/Gas
47 - 54
Brain/Gas
1.15
Mean Component/Gas Partition Coefficients at 25°C for Polymers
Used Commonly in Medical Applications:
Conductive rubber
14.0
Butyl rubber
7.7
Polyvinyl chloride
17.4
Polyethylene
1.3
Sevoflurane is nonflammable and nonexplosive as defined by the
requirements of
International Electrotechnical Commission 601-2-13.
Sevoflurane is a clear, colorless, stable liquid containing no
additives or chemical
stabilizers. Sevoflurane is nonpungent. It is miscible with ethanol,
ether, chloroform and
petroleum benzene, and it is slightly soluble in water. Sevoflurane is
stable when stored
under normal room lighting condition according to instructions.
INDICATIONS:
Sevoflurane is indicated for induction and maintenance of general
anesthesia in dogs.
DOSAGE AND ADMINISTRATION:
INSPIRED CONCENTRATION: The delivered concentration of Sevoflurane
should be known.
Since the depth of anesthesia may be altered easily and rapidly, only
vaporizers
producing predictable percentage concentrations of sevoflurane should
be used.
Sevoflurane should be vaporized using a precision vaporizer
specifically calibrated for
sevoflurane. Sevoflurane contains no stabilizer. Nothing in the drug
product alters
calibration or operation of these vaporizers. The administration of
general anesthesia
must be individualized based