国家: 马来西亚
语言: 英文
来源: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
MICONAZOLE NITRATE; HYDROCORTISONE ACETATE
DYNAPHARM (M) SDN BHD
MICONAZOLE NITRATE; HYDROCORTISONE ACETATE
15 gm
DYNAPHARM (M) SDN BHD
Consumer Medication Information Leaflet (RiMUP) MICORT CREAM Miconazole Nitrate / Hydrocortisone Acetate (2% / 1%) 1 What is in this leaflet 1. What Micort Cream is used for 2. How Micort Cream works 3. Before you use Micort Cream 4. How to use Micort Cream 5. While you are using it 6. Side effects 7. Storage and Disposal of Micort Cream 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision What Micort Cream is used for Treatment of inflamed conditions of the skin which may be caused by infection withcertain fungi and bacteria. How Micort Cream works Miconazole is an antifungal agent and may act by interferring with the permeability of the fungal cell membrane. It has a wide antifungal spectrum and possesses some antibacterial activity. Hydrocortisone when applied externally will produce anti-iflammatory and anti- allergic actions in the skin. Before you use Micort Cream - When you must not use it Do not use Micort Cream if you have history of sensitivity reaction to hydrocortisone or other topical corticosteroids or miconazole or other imidazole antifungal agents. Tuberculosis of the skin, and viral diseases, such as herpes simplex. Pregnancy and lactation It should not be used in pregnant women in large amounts or for prolonged period of time. - Before you start to use it You must tell your doctor if you: • are pregnant or breastfeeding. • are on Warfarin therapy. - Taking other medicines Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop. How to use Micort Cream - How much to use Apply a thin film of the cream to the affected area twice daily until lesion has completely disappeared. Once the inflammatory symptoms have disappeared (after about 7 days), treatment can be continued where necessary with antifungal alone. Follow all directions given to you by your doctor and pharmacist carefully. They may differ from the information contained in this leaflet. If you do not 阅读完整的文件
MICORT CREAM MAL19913383AZ DESCRIPTION: CREAM Colour : White Fragrance : Natural CONTENT: Miconazole Nitrate ........................... 2% w/w Hydrocortisone Acetate ...................... 1% w/w Preservative: Chlorocresol ................ 0.1% w/w PHARMACODYNAMICS: Miconazole is an imidazole antifungal agent and may act by interfering with the permeability of the fungal cell membrane. It has a wide antifungal spectrum and possesses some antibacterial activity. Hydrocortisone is an adrenocorticoid which when applied externally will produce anti-inflammatory and anti-allergic actions in the skin. It diffuses across cell membranes and complexes with specific cytoplasmic receptors. These complexes then enter the cell nucleus, bind to DNA (chromatin), and stimulate transcription of messenger RNA (mRNA) and subsequent protein synthesis of various enzymes thought to be ultimately responsible for anti-inflammatory effects of topical application of adrenocorticoids. PHARMACOKINETICS: When applied externally, there is very little absorption of Miconazole Nitrate through skin or mucous membranes. When applied externally, Hydrocortisone can be absorbed systematically and occlusion or use over extensive areas increases absorption of topical applied drug. Metabolism is mostly in the skin tissue. INDICATION: For the topical treatment of inflamed dermatoses where infection by susceptible organisms and inflammation coexist e.g. intertrigo, infected eczema, tinea pedis, tinea cruris, tinea corporis, tinea versicolor and cutaneous candidiasis. RECOMMENDED DOSE: Apply a thin film of the cream to the affected area twice daily until lesion has completely disappeared. Once the inflammatory symptoms have disappeared (after about 7 days), treatment can be continued where necessary with antifungal alone. CONTRAINDICATION: History of sensitivity reaction to Hydrocortisone or other topical corticosteroids or Miconazole or other imidazole antifungal agents. Tuberculosis of the skin, and viral diseases, e.g. herpes simplex, varicella, vacci 阅读完整的文件