MICORT CREAM

Страна: Малайзия

Език: английски

Източник: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Активна съставка:

MICONAZOLE NITRATE; HYDROCORTISONE ACETATE

Предлага се от:

DYNAPHARM (M) SDN BHD

INN (Международно Name):

MICONAZOLE NITRATE; HYDROCORTISONE ACETATE

Броя в опаковка:

15 gm

Произведено от:

DYNAPHARM (M) SDN BHD

Листовка

Consumer Medication Information Leaflet (RiMUP)
MICORT CREAM
Miconazole Nitrate / Hydrocortisone Acetate (2% / 1%)
1
What is in this leaflet
1.
What Micort Cream is used for
2.
How Micort Cream works
3.
Before you use Micort Cream
4.
How to use Micort Cream
5.
While you are using it
6.
Side effects
7.
Storage and Disposal of Micort
Cream
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10.
Date of revision
What Micort Cream is used for
Treatment of inflamed conditions of the
skin which may be caused by infection
withcertain fungi and bacteria.
How Micort Cream works
Miconazole is an antifungal agent and
may act by interferring with the
permeability of the fungal cell membrane.
It has a wide antifungal spectrum and
possesses some antibacterial activity.
Hydrocortisone when applied externally
will produce anti-iflammatory and anti-
allergic actions in the skin.
Before you use Micort Cream
-
When you must not use it
Do not use Micort Cream if you have
history of sensitivity reaction to
hydrocortisone or other topical
corticosteroids or miconazole or other
imidazole antifungal agents.
Tuberculosis of the skin, and viral
diseases, such as herpes simplex.
Pregnancy and lactation
It should not be used in pregnant women
in large amounts or for prolonged period
of time.
-
Before you start to use it
You must tell your doctor if you:
•
are pregnant or breastfeeding.
•
are on Warfarin therapy.
-
Taking other medicines
Tell your doctor if you are taking any
other medicines, including any that you
buy without a prescription from a
pharmacy, supermarket or health food
shop.
How to use Micort Cream
-
How much to use
Apply a thin film of the cream to the
affected area twice daily until lesion has
completely disappeared.
Once the inflammatory symptoms have
disappeared (after about 7 days),
treatment can be continued where
necessary with antifungal alone.
Follow all directions given to you by
your doctor and pharmacist carefully.
They may differ from the information
contained in this leaflet. If you do not

Данни за продукта

MICORT CREAM
MAL19913383AZ
DESCRIPTION:
CREAM
Colour
: White
Fragrance
: Natural
CONTENT:
Miconazole Nitrate ........................... 2% w/w
Hydrocortisone Acetate ...................... 1% w/w
Preservative: Chlorocresol ................ 0.1% w/w
PHARMACODYNAMICS:
Miconazole is an imidazole antifungal agent and may act by interfering
with the permeability of the fungal cell membrane. It
has a wide antifungal spectrum and possesses some antibacterial
activity.
Hydrocortisone is an adrenocorticoid which when applied externally
will produce anti-inflammatory and anti-allergic actions
in the skin. It diffuses across cell membranes and complexes with
specific cytoplasmic receptors. These complexes then
enter the cell nucleus, bind to DNA (chromatin), and stimulate
transcription of messenger RNA (mRNA) and subsequent
protein synthesis of various enzymes thought to be ultimately
responsible for anti-inflammatory effects of topical application
of adrenocorticoids.
PHARMACOKINETICS:
When applied externally, there is very little absorption of Miconazole
Nitrate through skin or mucous membranes.
When applied externally, Hydrocortisone can be absorbed systematically
and occlusion or use over extensive areas increases
absorption of topical applied drug. Metabolism is mostly in the skin
tissue.
INDICATION:
For the topical treatment of inflamed dermatoses where infection by
susceptible organisms and inflammation coexist e.g.
intertrigo, infected eczema, tinea pedis, tinea cruris, tinea
corporis, tinea versicolor and cutaneous candidiasis.
RECOMMENDED DOSE:
Apply a thin film of the cream to the affected area twice daily until
lesion has completely disappeared. Once the
inflammatory symptoms have disappeared (after about 7 days), treatment
can be continued where necessary with antifungal
alone.
CONTRAINDICATION:
History of sensitivity reaction to Hydrocortisone or other topical
corticosteroids or Miconazole or other imidazole antifungal
agents. Tuberculosis of the skin, and viral diseases, e.g. herpes
simplex, varicella, vacci