Quốc gia: Malaysia
Ngôn ngữ: Tiếng Anh
Nguồn: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
PREDNISOLONE
IDAMAN PHARMA MANUFACTURING SDN BHD
PREDNISOLONE
30 Tablets; 1000 Tablets
IDAMAN PHARMA MANUFACTURING SDN BHD
IDAMAN PHARMA PREDNISOLONE TABLET 5MG Prednisolone (5mg) 1 _CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ WHAT IS IN THIS LEAFLET 1. What Idaman Pharma Prednisolone Tablet 5mg is used for 2. How Idaman Pharma Prednisolone Tablet 5mg works 3. Before you use Idaman Pharma Prednisolone Tablet 5mg 4. How to use Idaman Pharma Prednisolone Tablet 5mg 5. While you are using it 6. Side Effects 7. Storage and Disposal of Idaman Pharma Prednisolone Tablet 5mg 8. Product Description 9. Product Registration Holder and Manufacturer 10. Date of Revision WHAT IDAMAN PHARMA PREDNISOLONE TABLET 5MG IS USED FOR Idaman Pharma Prednisolone Tablet 5mg is used in the treatment of many different conditions. Some of these conditions include: severe allergies, severe or chronic asthma, skin problems, arthritis, inflammatory diseases of the bowel, cancer and "auto-immune" diseases. It is also used to prevent or reduce the symptoms of inflammation (such as swelling, redness, pain, tenderness or itching) in any part of the body. These symptoms can occur in response to injury or can be caused by many different conditions. HOW IDAMAN PHARMA PREDNISOLONE TABLET 5MG WORKS Prednisolone belongs to a group of medicines called corticosteroids which are a synthetic version of a naturally occurring body hormone called cortisol. Idaman Pharma Prednisolone Tablet 5mg works by entering inflammatory cells and blocking the inflammatory reaction. This medicine is only able to prevent or reduce symptoms of your condition, it does not cure it. BEFORE YOU USE IDAMAN PHARMA PREDNISOLONE TABLET 5MG - _When you must not use it _ Do not take Idaman Pharma Prednisolone Tablet 5mg if you have ever had an allergic reaction to: • prednisolone or prednisone • any of the ingredients listed at the end of this leaflet. Symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty in breathing; swelling of the face, lips, tongue or any other parts of the body; rash, itching or hives on the skin. Do not take it if you have a current seriou Đọc toàn bộ tài liệu
—————IDAMAN PHARMA PREDNISOLONE TABLET 5MG————— PRODUCT DESCRIPTION Clean, dry, round, uniform, flat, bevel edged tablets, scored on one side and white in colour. EACH TABLET CONTAINS : Prednisolone 5mg. PHARMACODYNAMICS Prednisolone diffuses across cell membranes and forms complexes with specific cytoplasmic receptors. These complexes then enter the cell nucleus, bind to DNA (chromatin) and stimulate transcription of mRNA and subsequent protein synthesis of various enzymes thought to be ultimately responsible for two categories of effects of its systemic use. GLUCOCORTICOID EFFECTS (POTENT) i) ANTI-INFLAMMATORY - Inhibition of phagocytosis, leukocyte migration and capillary dilatation occur; Lysosomal membrane stabilization and possibly decreased prostaglandin/thromboxane synthesis may be mediated through the altered activity of enzymes which regulates the phospholipid content of cell membranes. ii) IMMUNOSUPPRESSANT - Prevention or suppression of cell mediated (delayed hypersensitivity) immune reactions may be related to the anti- inflammatory actions of prednisolone; mechanism for anti-mitotic effects and for decreased growth are not known. iii) METABOLIC - Protein catabolism provides amino acids for gluconeogenesis, which, along with the decreased peripheral utilisation of glucose, leads to increased glycogen storage in the liver, increased blood glucose concentrations and insulin resistance. Lipolysis occurs and with excessive use of prednisolone, an abnormal redistribution of fat can occur. MINERALOCORTICOID EFFECTS (WEAK) - Water and electrolyte balance - Sodium reabsorption, potassium and hydrogen excretion, along with subsequent water retention, are mediated through an action of mineralocorticoids on the renal distal tubule which facilitates sodium transport. Cation transport in other secretory cells is similarly affected; excretion of water and electrolytes by the large intestine, salivary and sweat glands are also altered, but to a lesser extent. PHARMACOKINETICS Prednisolone is rea Đọc toàn bộ tài liệu