Quốc gia: Malaysia
Ngôn ngữ: Tiếng Anh
Nguồn: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
MOMETASONE FUROATE
ORGANON MALAYSIA SDN. BHD.
MOMETASONE FUROATE
30ml mL; 30 ml mL
Delpharm Montreal Inc.
_CONSUMER_ _ _ _MEDICATION_ _ _ _INFORMATION_ _ _ _LEAFLET(RIMUP)_ _ _ ELOMET ® LOTION Mometasone Furoate (0.1% w/w) 1 Copyright 2021 Organon group of companies. All rights reserved. WHAT IS IN THIS LEAFLET 1. What ELOMET LOTION is used for 2. How ELOMET LOTION works 3. Before you take ELOMET LOTION 4. How to take ELOMET LOTION 5. While you are taking ELOMET LOTION 6. Side effects 7. Storage and Disposal of ELOMET LOTION 8. Product description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT ELOMET LOTION IS USED FOR ELOMET LOTION is used to reduce inflammation and itchiness caused by certain skin condtions including the scalp, that are responsive to corticosteroids. HOW ELOMET LOTION WORKS ELOMET LOTION is one of a group of medicines called topical corticosteroids. Mometasone furoate have anti- inflammatory, anti itching and blood vessel narrowing action. BEFORE YOU USE ELOMET LOTION _- When you must not use it _ Do not use ELOMET LOTION if you are allergic (hypersensitive) to mometasone furoate, or to any of the other ingredients of ELOMET LOTION or to other similar medicines. Side effects that may happen with oral or injectable corticosteroids may also occur with topical corticosteroids, especially in infants and children. Ask your doctor or pharmacist if you are not sure. _-_ _ _ _Before you start to use it _ PREGNANCY AND BREAST-FEEDING You should tell your doctor if you are pregnant or breast- feeding, before you start using ELOMET LOTION _-_ _ _ _Taking other medicines _ TELL YOUR DOCTOR OR PHARMACIST IF YOU ARE USING OTHER CREAMS, OINTMENTS OR LOTIONS OR TAKING ANY OTHER MEDICINES. THIS INCLUDES ANY THAT YOU GET WITHOUT A PRESCRIPTION FROM YOUR PHARMACY, SUPERMARKET OR HEALTH FOOD SHOP. HOW TO USE ELOMET LOTION _-_ _ _ _How much to use _ Always use ELOMET LOTION exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. A few drops of ELOMET LOTION should be gently massaged into the affected skin area including the scalp until the me Đọc toàn bộ tài liệu
LPC-MK0887-MTL-082017 ELOMET® LOTION 0.1% Brand of mometasone furoate FOR DERMATOLOGIC USE ONLY DESCRIPTION: ELOMET Lotion 0.1% is a colorless to off-white lotion. Each gram of ELOMET Lotion 0.1% contains 1 mg mometasone furoate, isopropyl alcohol, hydroxypropylcellulose, sodium phosphate monobasic dihydrate, propylene glycol, purified water and phosphoric acid, if needed, to adjust the pH. ACTION: Mometasone furoate, a synthetic corticosteroid, exhibits anti-inflammatory, antipruritic and vasoconstrictive properties. PHARMACOLOGY: PRE-CLINICAL DATA: PHARMACODYNAMICS The pharmacologic profile of mometasone furoate was determined by standard laboratory methods. Relative to betamethasone valerate, anti-inflammatory activity and anti-psoriatic activity of mometasone furoate was evaluated in mice and guinea pigs, respectively. Hypothalamic-pituitary-adrenal (HPA) axis suppression, thymolysis and skin atrophy were evaluated in mice. In the croton oil assay in mice, mometasone furoate (ED 50 = 0.02 μg/ear) was equipotent to betamethasone valerate after single application, and was approximately eight times as potent as betamethasone valerate after five daily applications (ED 50 = 0.002 μg/ear/day vs 0.014 μg/ear/day). In guinea pigs, mometasone furoate was approximately twice as potent as betamethasone valerate in reducing M. Ovalis-induced epidermal acanthosis after 14 daily applications. With respect to other pharmacologic activities commonly associated with corticosteroids, mometasone furoate (ED 50 = 5.3 μg/ear/day) was less potent than betametasone valerate (ED 50 = 3.1 μg/ear/day) in suppressing the HPA axis in mice after five daily application. In the thymolysis assay, mometasone furoate (ED 50 = 26.6 μg/ear/day) was approximately two times as potent as betamethasone valerate (ED 50 = 51.6 μg/ear/day) when applied topically, and following subcutaneous administration for five days, mometasone furoate (ED 50 = 11.2 μg/mouse) was approximately six times as potent as betamethasone valerate (ED 50 = 59.8 μg/ Đọc toàn bộ tài liệu