ELOMET LOTION 0.1%

देश: मलेशिया

भाषा: अंग्रेज़ी

स्रोत: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

सक्रिय संघटक:

MOMETASONE FUROATE

थमां उपलब्ध:

ORGANON MALAYSIA SDN. BHD.

INN (इंटरनेशनल नाम):

MOMETASONE FUROATE

पैकेज में यूनिट:

30ml mL; 30 ml mL

द्वारा बनाया गया:

Delpharm Montreal Inc.

सूचना पत्रक

_CONSUMER_
_ _
_MEDICATION_
_ _
_INFORMATION_
_ _
_LEAFLET(RIMUP)_
_ _
ELOMET
® LOTION
Mometasone Furoate (0.1% w/w)
1
Copyright 2021 Organon group of companies. All rights reserved.
WHAT IS IN THIS LEAFLET
1.
What ELOMET LOTION is
used for
2.
How ELOMET LOTION
works
3.
Before you take ELOMET
LOTION
4.
How to take ELOMET
LOTION
5.
While you are taking
ELOMET LOTION
6.
Side effects
7.
Storage and Disposal of
ELOMET LOTION
8.
Product description
9.
Manufacturer and Product
Registration Holder
10.
Date of revision
WHAT ELOMET LOTION IS
USED FOR
ELOMET LOTION is used to
reduce inflammation and
itchiness caused by certain skin
condtions including the scalp,
that are responsive to
corticosteroids.
HOW ELOMET LOTION
WORKS
ELOMET LOTION is one of a
group of medicines called topical
corticosteroids.
Mometasone furoate have anti-
inflammatory, anti itching and
blood vessel narrowing action.
BEFORE YOU USE ELOMET
LOTION
_- When you must not use it _
Do not use ELOMET LOTION
if you are allergic
(hypersensitive) to mometasone
furoate, or to any of the other
ingredients of ELOMET
LOTION or to other similar
medicines.
Side effects that may happen
with oral or injectable
corticosteroids may also occur
with topical corticosteroids,
especially in infants and children.
Ask your doctor or pharmacist if
you are not sure.
_-_
_ _
_Before you start to use it _
PREGNANCY AND BREAST-FEEDING
You should tell your doctor if
you are pregnant or breast-
feeding, before you start using
ELOMET LOTION
_-_
_ _
_Taking other medicines _
TELL YOUR DOCTOR OR PHARMACIST
IF YOU ARE USING OTHER CREAMS,
OINTMENTS OR LOTIONS OR TAKING
ANY OTHER MEDICINES. THIS
INCLUDES ANY THAT YOU GET
WITHOUT A PRESCRIPTION FROM
YOUR PHARMACY, SUPERMARKET
OR HEALTH FOOD SHOP.
HOW TO USE ELOMET
LOTION
_-_
_ _
_How much to use _
Always use ELOMET LOTION
exactly as your doctor has told
you. You should check with your
doctor or pharmacist if you are
not sure.
A few drops of ELOMET
LOTION should be gently
massaged into the affected skin
area including the scalp until the
me

उत्पाद विशेषताएं

LPC-MK0887-MTL-082017
ELOMET® LOTION 0.1%
Brand of mometasone furoate
FOR DERMATOLOGIC USE ONLY
DESCRIPTION:
ELOMET Lotion 0.1% is a colorless to off-white lotion. Each gram of
ELOMET Lotion 0.1%
contains
1 mg
mometasone
furoate,
isopropyl
alcohol,
hydroxypropylcellulose,
sodium
phosphate monobasic dihydrate, propylene glycol, purified water and
phosphoric acid, if
needed, to adjust the pH.
ACTION:
Mometasone furoate, a synthetic corticosteroid, exhibits
anti-inflammatory, antipruritic and
vasoconstrictive properties.
PHARMACOLOGY:
PRE-CLINICAL DATA:
PHARMACODYNAMICS
The pharmacologic profile of mometasone furoate was determined by
standard laboratory
methods. Relative to betamethasone valerate, anti-inflammatory
activity and anti-psoriatic
activity of mometasone furoate was evaluated in mice and guinea pigs,
respectively.
Hypothalamic-pituitary-adrenal (HPA) axis suppression, thymolysis and
skin atrophy were
evaluated in mice.
In the croton oil assay in mice, mometasone furoate (ED
50
= 0.02 μg/ear) was equipotent to
betamethasone valerate after single application, and was approximately
eight times as
potent as betamethasone valerate after five daily applications (ED
50
= 0.002 μg/ear/day vs
0.014 μg/ear/day). In guinea pigs, mometasone furoate was
approximately twice as potent
as betamethasone valerate in reducing M. Ovalis-induced epidermal
acanthosis after 14
daily applications.
With respect to other pharmacologic activities commonly associated
with corticosteroids,
mometasone furoate (ED
50
= 5.3 μg/ear/day) was less potent than betametasone valerate
(ED
50
= 3.1 μg/ear/day) in suppressing the HPA axis in mice after five
daily application. In
the thymolysis assay, mometasone furoate (ED
50
= 26.6 μg/ear/day) was approximately two
times as potent as betamethasone valerate (ED
50
= 51.6 μg/ear/day) when applied topically,
and following subcutaneous administration for five days, mometasone
furoate (ED
50
=
11.2 μg/mouse) was approximately six times as potent as betamethasone
valerate (ED
50
=
59.8 μg/