Ülke: Yeni Zelanda
Dil: İngilizce
Kaynak: Medsafe (Medicines Safety Authority)
Pioglitazone hydrochloride 49.6mg equivalent to Pioglitazone 45 mg;
Douglas Pharmaceuticals Limited
Pioglitazone hydrochloride 49.6 mg (equivalent to Pioglitazone 45 mg)
45 mg
Tablet
Active: Pioglitazone hydrochloride 49.6mg equivalent to Pioglitazone 45 mg Excipient: Carmellose calcium Hyprolose Lactose monohydrate Magnesium stearate
Aluminium foil, Alu/Alu 28 tablets, 28 tablets
Prescription
Prescription
Biocon Limited
Package - Contents - Shelf Life: Aluminium foil, Alu/Alu 28 tablets - 28 tablets - 36 months from date of manufacture stored at or below 25°C protect from light and moisture
2006-06-22
DATA SHEET PIZACCORD 15 mg, 30 mg and 45 mg Tablets The active ingredient in PIZACCORD tablets is pioglitazone as pioglitazone hydrochloride. Chemically, pioglitazone hydrochloride is [(±)-5-[[4-[2-(5-ethyl-2- pyridinyl)ethoxy]phenyl]methyl]-2,4-] thiazolidinedione hydrochloride. The empirical formula is C 19 H 20 N 2 O 3 S•HCl which corresponds to a molecular weight of 392.90 daltons. The CAS number for pioglitazone HCl is 112529-15-4. The CAS number for pioglitazone free base is 111025-46-8. DESCRIPTION Pioglitazone is an odourless, white crystalline powder that is soluble in N,N- dimethylformamide, slightly soluble in anhydrous ethanol, very slightly soluble in acetone and acetonitrile, practically insoluble in water and insoluble in ether. Each tablet contains 15, 30 or 45 mg of pioglitazone (as pioglitazone hydrochloride). The tablets also contain hydroxypropylcellulose, carmellose calcium, lactose monohydrate and magnesium stearate. PIZACCORD 15 mg tablets are round, white, biconvex, uncoated tablets embossed with ‘PIO’ on one side and ‘15’ on the other side. PIZACCORD 30 mg tablets are round, white, flat, uncoated tablets embossed with ‘PIO’ on one side and ‘30’ on the other side. PIZACCORD 45 mg tablets are round, white, flat, uncoated tablets embossed with ‘PIO’ on one side and ‘45’ on the other side. Do not halve the tablets. Dose equivalence when a tablet is divided has not been established PHARMACOLOGY Pioglitazone is an oral antidiabetic agent that acts primarily by decreasing insulin resistance. Pharmacological studies indicate that pioglitazone improves sensitivity to insulin in muscle and adipose tissue and inhibits hepatic gluconeogenesis. Pioglitazone improves glycaemic control while reducing ci Belgenin tamamını okuyun