Ülke: Malezya
Dil: İngilizce
Kaynak: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
PANTOPRAZOLE SODIUM SESQUIHYDRATE
HEALOL PHARMACEUTICALS SDN. BHD.
PANTOPRAZOLE SODIUM SESQUIHYDRATE
7 blister x 14 Tablets
MICRO LABS LIMITED
PANTOMAC _Consumer Medication Information Leaflet (RiMUP)_ Pantoprazole Gastro- Resistant Tablets 40mg 1 WHAT IS IN THIS LEAFLET What Pantomac is used for How Pantomac works Before you use Pantomac How to use Pantomac While you are using it Side effects Storage and Disposal of Pantomac Product Description Manufacturer and Product Registration Holder Date of revision Serial number WHAT IS PANTOMAC USED FOR Pantoprazole is used to treat adults and adolescents 12 years of age and above for -Reflux esophagitis. An inflammation of your oesophagus (the tube which connects your throat to your stomach) accompanied by the regurgitation of stomach acid. Pantoprazole is used to treat adults for - An infection with a bacterium called Helicobacter pylori in patients with duodenal ulcers and stomach ulcers in combination with two antibiotics (eradication therapy). The aim is to get rid of the bacteria and so reduce the likelihood of these ulcers returning. - Stomach and duodenal ulcers. - Zollinger-Ellison-Syndrome and other conditions producing too much acid in the stomach. HOW PANTOMAC WORKS Pantomac contains the active substance Pantoprazole. Pantoprazole is a selective “proton pump inhibitor”, a medicine which reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine. BEFORE YOU USE PANTOMAC _-When you must not use it _ - If you are allergic to pantoprazole or to any of the other ingredients of this medicine. - If you are allergic to medicines containing other proton pump inhibitors. _-Before you start to use it _ Talk to your doctor, pharmacist or nurse before taking Pantoprazole - If you have severe liver problems. Please tell your doctor if you ever had problems with your liver in the past. He will check your liver enzymes more frequently, especially when you are taking Pantoprazole as a long-term treatment. In the case of a rise of liver enzymes the treatment should be stopped. - If you have reduced body stores or risk factors for reduced vitamin Belgenin tamamını okuyun
PANTOPRAZOLE GASTRO RESISTANT TABLETS 40MG PANTOMAC NAME AND STRENGTH OF ACTIVE INGREDIENT: Each gastro-resistant tablet contains: Pantoprazole Sodium Sesquihydrate equivalent to Pantoprazole …..40mg PRODUCT DESCRIPTION: Yellow colored, enteric coated, oval biconvex tablets plain on both the side. PHARMACOLOGY: _PHARMACODYNAMICS:_ Pantoprazole is substituted benzimidazoles which inhibits the secretion of hydrochloric acid in the stomach by specific blockade of the proton pumps of the parietal cells. Pantoprazole is converted to its active form in the acidic environment in the parietal cells where it inhibits the H+, K+-ATPase enzyme, i.e. the final stage in the production of hydrochloric acid in the stomach. The inhibition is dose-dependent and affects both basal and stimulated acid secretion. In most patients, freedom from symptoms is achieved within 2 weeks. As with other proton pump inhibitors and H2 receptor inhibitors, treatment with pantoprazole reduces acidity in the stomach and thereby increases gastrin in proportion to the reduction in acidity. The increase in gastrin is reversible. Since pantoprazole binds to the enzyme distal to the cell receptor level, it can inhibit hydrochloric acid secretion independently of stimulation by other substances (acetylcholine, histamine, and gastrin). The effect is the same whether the product is given orally or intravenously. During treatment with antisecretory medicinal products, serum gastrin increases in response to the decreased acid secretion. Also CgA increases due to decreased gastric acidity. The increased CgA level may interfere with investigations for neuroendocrine tumours. Available published evidence suggests that proton pump inhibitors should be discontinued between 5 days and 2 weeks prior to CgA measurements. This is to allow CgA levels that might be spuriously elevated following PPI treatment to return to reference range. _PHARMACOKINETICS:_ _ABSORPTION: _ Pantoprazole is rapidly absorbed and the maximal plasma concentration is achieved even after on Belgenin tamamını okuyun