Pantomac (Pantoprazole Gastro Resistant Tablet 40 mg)

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

PANTOPRAZOLE SODIUM SESQUIHYDRATE

Boleh didapati daripada:

HEALOL PHARMACEUTICALS SDN. BHD.

INN (Nama Antarabangsa):

PANTOPRAZOLE SODIUM SESQUIHYDRATE

Unit dalam pakej:

7 blister x 14 Tablets

Dikeluarkan oleh:

MICRO LABS LIMITED

Risalah maklumat

PANTOMAC
_Consumer Medication Information Leaflet (RiMUP)_
Pantoprazole Gastro- Resistant Tablets 40mg
1
WHAT IS IN THIS LEAFLET
What Pantomac is used for
How Pantomac works
Before you use Pantomac
How to use Pantomac
While you are using it
Side effects
Storage and Disposal of Pantomac
Product Description
Manufacturer
and
Product
Registration Holder
Date of revision
Serial number
WHAT IS PANTOMAC USED FOR
Pantoprazole is used to treat adults
and adolescents 12 years of age and
above for
-Reflux esophagitis. An inflammation
of your oesophagus (the tube which
connects your throat to your stomach)
accompanied by the regurgitation of
stomach acid.
Pantoprazole is used to treat adults for
- An infection with a bacterium called
Helicobacter pylori in patients with
duodenal ulcers and stomach ulcers in
combination
with
two
antibiotics
(eradication therapy). The aim is to
get rid of the bacteria and so reduce
the
likelihood
of
these
ulcers
returning.
- Stomach and duodenal ulcers.
- Zollinger-Ellison-Syndrome and
other conditions producing too much
acid in the stomach.
HOW PANTOMAC WORKS
Pantomac
contains
the
active
substance Pantoprazole. Pantoprazole
is a selective “proton pump inhibitor”,
a medicine which reduces the amount
of acid produced in your stomach. It
is
used
for
treating
acid-related
diseases of the stomach and intestine.
BEFORE YOU USE PANTOMAC
_-When you must not use it _
- If you are allergic to pantoprazole
or to any of the other ingredients of
this medicine.
- If you are allergic to medicines
containing
other
proton
pump
inhibitors.
_-Before you start to use it _
Talk to your doctor, pharmacist or
nurse before taking Pantoprazole
- If you have severe liver problems.
Please tell your doctor if you ever had
problems with your liver in the past.
He
will
check
your
liver
enzymes
more frequently, especially when
you are taking Pantoprazole as a
long-term treatment. In the case of a
rise of liver enzymes the treatment
should be stopped.
- If you have reduced body stores or
risk factors for reduced vitamin

Ciri produk

PANTOPRAZOLE GASTRO RESISTANT TABLETS 40MG
PANTOMAC
NAME AND STRENGTH OF ACTIVE INGREDIENT:
Each gastro-resistant tablet contains:
Pantoprazole Sodium Sesquihydrate equivalent to Pantoprazole …..40mg
PRODUCT DESCRIPTION:
Yellow colored, enteric coated, oval biconvex tablets plain on both
the side.
PHARMACOLOGY:
_PHARMACODYNAMICS:_
Pantoprazole is substituted benzimidazoles which inhibits the
secretion of hydrochloric acid in the stomach by specific blockade of
the proton pumps of the parietal cells.
Pantoprazole is converted to its active form in the acidic environment
in the parietal cells where it inhibits the H+, K+-ATPase
enzyme, i.e. the final stage in the production of hydrochloric acid in
the stomach. The inhibition is dose-dependent and affects both
basal and stimulated acid secretion. In most patients, freedom from
symptoms is achieved within 2 weeks. As with other proton
pump inhibitors and H2 receptor inhibitors, treatment with
pantoprazole reduces acidity in the stomach and thereby increases
gastrin in proportion to the reduction in acidity. The increase in
gastrin is reversible. Since pantoprazole binds to the enzyme distal
to the cell receptor level, it can inhibit hydrochloric acid secretion
independently of stimulation by other substances (acetylcholine,
histamine, and gastrin). The effect is the same whether the product is
given orally or intravenously.
During treatment with antisecretory medicinal products, serum gastrin
increases in response to the decreased acid secretion. Also
CgA increases due to decreased gastric acidity. The increased CgA
level may interfere with investigations for neuroendocrine
tumours.
Available published evidence suggests that proton pump inhibitors
should be discontinued between 5 days and 2 weeks prior to
CgA measurements. This is to allow CgA levels that might be spuriously
elevated following PPI treatment to return to reference
range.
_PHARMACOKINETICS:_
_ABSORPTION: _
Pantoprazole is rapidly absorbed and the maximal plasma concentration
is achieved even after on