Ülke: Malezya
Dil: İngilizce
Kaynak: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
ISOFLURANE
UNIMED SDN BHD
ISOFLURANE
100 ml; 250 ml
Piramal Pharma Limited
Not Applicable Belgenin tamamını okuyun
Predication: Premedication drugs should be selected according to the needs of the patients. The ventilatory depressant effect of isolfuarne should be taken into account. As Isoflurane causes increased heart rate and only weak stimulation of secretions, the use of anticholinergic drugs is a matter of choice. with 70% N O 2 Mid-twenties 1.25 to 1.30% 0.49 to 0.63 Mid-sixties 1.00 to 1.10% 0.33 to 0.41 Induction: As isoflurane has a mild pungency, inhalation should usually by preceded by the use of short-acting barbiturate, or other intravenous induction agent, to prevent coughing. Salivation and coughing may be troublesome in small children inducted with Isoflurane. Alternatively, Isoflurane with oxygen or with an oxygen/nitrous oxide mixture may be administered. It is recommended that induction with Isoflurane be initiated at a concentration of 0.5%. Concentrations of 1.5 3.0% usually produce surgical anesthesia in seven (7) ten (10) minutes. Blood pressure decreases during induction but this may compensated by surgical stimulation. Mid-forties 1.10 to 1.20% 0.43 to 0.57 Ave. Conc. Induced hypotension can be achieved by artificially ventilating patients with Isoflurane 2.5 4.0% Maintenance: adequate anesthesia for surgery may be sustained with an inspired Isoflurane concentration of 1.0% to 2.5% in an oxygen/70% nitrous oxide mixture. Additional inspired Isoflurane (0.5% to 1.0%) will be required with lower nitrous oxide levels, or when Isoflurane is given with oxygen alone or with air/oxygen mixtures. Blood pressure decreases during maintenance anesthesia in relation to depth of anaesthesia. That is, blood pressure is inversely related to the Isoflurane concentration. Provided there are no other complicating factors this is probably due to peripheral vasodilation. Cardiac rhythm remains stable. Excessive falls in blood pressure may be due to the depth of anesthesia and in such circumstances can be corrected by reducing the inspired Isoflurane concentration. Recovery: The concentration of Isoflurane can be reduced Belgenin tamamını okuyun