ISORANE (Isoflurane Inhalation Liquid 100% VV)

البلد: ماليزيا

اللغة: الإنجليزية

المصدر: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

العنصر النشط:

ISOFLURANE

متاح من:

UNIMED SDN BHD

INN (الاسم الدولي):

ISOFLURANE

الوحدات في الحزمة:

100 ml; 250 ml

المصنعة من قبل:

Piramal Pharma Limited

نشرة المعلومات

Not Applicable

خصائص المنتج

Predication: Premedication drugs should be selected
according to the needs of the patients. The ventilatory
depressant effect of isolfuarne should be taken into account.
As Isoflurane causes increased heart rate and only weak
stimulation of secretions, the use of anticholinergic drugs is a
matter of choice.
with 70% N O
2
Mid-twenties
1.25 to 1.30%
0.49 to 0.63
Mid-sixties
1.00 to 1.10%
0.33 to 0.41
Induction: As isoflurane has a mild pungency, inhalation
should usually by preceded by the use of short-acting
barbiturate, or other intravenous induction agent, to prevent
coughing. Salivation and coughing may be troublesome in
small children inducted with Isoflurane. Alternatively,
Isoflurane with oxygen or with an oxygen/nitrous oxide
mixture may be administered. It is recommended that
induction with Isoflurane be initiated at a concentration of
0.5%. Concentrations of 1.5 3.0% usually produce surgical
anesthesia in seven (7) ten (10) minutes. Blood pressure
decreases during induction but this may compensated by
surgical stimulation.
Mid-forties
1.10 to 1.20%
0.43 to 0.57
Ave. Conc.
Induced hypotension can be achieved by artificially
ventilating patients with Isoflurane 2.5 4.0%
Maintenance: adequate
anesthesia for surgery may be
sustained with an inspired Isoflurane concentration of 1.0% to
2.5% in an oxygen/70% nitrous oxide mixture. Additional
inspired Isoflurane (0.5% to 1.0%) will be required with lower
nitrous oxide levels, or when Isoflurane is given with oxygen
alone or with air/oxygen mixtures. Blood pressure decreases
during maintenance anesthesia in relation
to depth of anaesthesia. That is, blood pressure is inversely
related to the Isoflurane concentration. Provided there are no
other complicating factors this is probably due to peripheral
vasodilation. Cardiac rhythm remains stable. Excessive falls
in blood pressure may be due to the depth of anesthesia and
in such circumstances can be corrected by reducing the
inspired Isoflurane concentration.
Recovery: The concentration of Isoflurane can be reduced