Nchi: Israeli
Lugha: Kiingereza
Chanzo: Ministry of Health
PIPERACILLIN AS SODIUM; TAZOBACTAM AS SODIUM
PHARMALOGIC LTD
J01CG02
POWDER FOR SOLUTION FOR INFUSION
PIPERACILLIN AS SODIUM 4 G; TAZOBACTAM AS SODIUM 500 MG
I.V
Required
PANPHARMA, FRANCE
TAZOBACTAM
TAZOBACTAM
Antibiotic for the treatment of systemic and/or local bacterial infections caused by susceptible organisms. Pipoeracillin/tazobactam in combination with an aminoglycoside is indicated for suspected bacterial infections in neutropenic adults or children above 2 years . Appencicitis complicated by rupture with peritonitis and/or abscess formation in children aged 2-12 years.
2017-06-30
PRESCRIBING INFORMATION 1. NAME OF THE MEDICINAL PRODUCT PIPERACILLIN/TAZOBACTAM PANPHARMA 2 G/250 MG PIPERACILLIN/TAZOBACTAM PANPHARMA 4 G/500 MG POWDER FOR SOLUTION FOR INFUSION 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Each vial contains: Piperacillin (as sodium) 2 g Tazobactam (as sodium) 250 mg (108 mg of sodium i.e., 4.69 mmol sodium/vial) Each vial contains: Piperacillin (as sodium) 4 g Tazobactam (as sodium) 500 mg (216 mg of sodium i.e., 9.36 mmol sodium/vial) 3. PHARMACEUTICAL FORM Powder for solution for infusion To reduce the development of drug-resistant bacteria and maintain the effectiveness of Piperacillin/ Tazobactam Panpharma (piperacillin and tazobactam) injection and other antibacterial drugs, Piperacillin/Tazobactam Panpharma (piperacillin and tazobactam) should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION Piperacillin/Tazobactam Panpharma (Piperacillin/Tazobactam for Injection) is an injectable antibacterial combination product consisting of the semisynthetic antibiotic piperacillin sodium and the beta- lactamase inhibitor tazobactam sodium for intravenous administration. Piperacillin sodium is derived from D( - )- α -aminobenzyl-penicillin. The chemical name of piperacillin sodium is sodium (2S,5R,6R)-6-[(R)-2-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)-2- phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate. The chemical formula is C 23 H 26 N 5 NaO 7 S and the molecular weight is 539.5. The chemical structure of piperacillin sodium is: Tazobactam sodium, a derivative of the penicillin nucleus, is a penicillanic acid sulfone. Its chemical name is sodium (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-methyl)-4-thia-1- azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide. The chemical formula is C 10 H 11 N 4 NaO 5 S and the molecular weight is 322.3. The chemical structure of tazobactam sodium is: 4. CLINICAL PARTICULARS 4.1 INDICATIONS Piperacillin/tazobactam is indicated for the Soma hati kamili