PIPERACILLIN TAZOBACTAM PANPHARMA 4G500MG

Pays: Israël

Langue: anglais

Source: Ministry of Health

Ingrédients actifs:

PIPERACILLIN AS SODIUM; TAZOBACTAM AS SODIUM

Disponible depuis:

PHARMALOGIC LTD

Code ATC:

J01CG02

forme pharmaceutique:

POWDER FOR SOLUTION FOR INFUSION

Composition:

PIPERACILLIN AS SODIUM 4 G; TAZOBACTAM AS SODIUM 500 MG

Mode d'administration:

I.V

Type d'ordonnance:

Required

Fabriqué par:

PANPHARMA, FRANCE

Groupe thérapeutique:

TAZOBACTAM

Domaine thérapeutique:

TAZOBACTAM

indications thérapeutiques:

Antibiotic for the treatment of systemic and/or local bacterial infections caused by susceptible organisms. Pipoeracillin/tazobactam in combination with an aminoglycoside is indicated for suspected bacterial infections in neutropenic adults or children above 2 years . Appencicitis complicated by rupture with peritonitis and/or abscess formation in children aged 2-12 years.

Date de l'autorisation:

2017-06-30

Résumé des caractéristiques du produit

PRESCRIBING INFORMATION
1.
NAME OF THE MEDICINAL PRODUCT
PIPERACILLIN/TAZOBACTAM PANPHARMA 2 G/250 MG
PIPERACILLIN/TAZOBACTAM PANPHARMA 4 G/500 MG
POWDER FOR SOLUTION FOR INFUSION
2.
QUALITATIVE AND QUANTITATIVE COMPOSITION
Each vial contains:
Piperacillin (as sodium) 2 g
Tazobactam (as sodium) 250 mg
(108 mg of sodium i.e., 4.69 mmol sodium/vial)
Each vial contains:
Piperacillin (as sodium) 4 g
Tazobactam (as sodium) 500 mg
(216 mg of sodium i.e., 9.36 mmol sodium/vial)
3.
PHARMACEUTICAL FORM
Powder for solution for infusion
To reduce the development of drug-resistant bacteria and maintain the
effectiveness of Piperacillin/
Tazobactam Panpharma (piperacillin and tazobactam) injection and other
antibacterial drugs,
Piperacillin/Tazobactam Panpharma (piperacillin and tazobactam) should
be used only to treat or
prevent infections that are proven or strongly suspected to be caused
by bacteria.
DESCRIPTION
Piperacillin/Tazobactam Panpharma (Piperacillin/Tazobactam for
Injection) is an injectable antibacterial
combination product consisting of the semisynthetic antibiotic
piperacillin sodium and the beta-
lactamase inhibitor tazobactam sodium for intravenous administration.
Piperacillin sodium is derived from D( - )-
α
-aminobenzyl-penicillin. The chemical name of
piperacillin sodium is sodium
(2S,5R,6R)-6-[(R)-2-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-
phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate.
The
chemical formula is C
23
H
26
N
5
NaO
7
S and the molecular weight is 539.5.
The chemical structure of piperacillin sodium is:
Tazobactam sodium, a derivative of the penicillin nucleus, is a
penicillanic acid sulfone. Its
chemical name is sodium
(2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-methyl)-4-thia-1-
azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide. The chemical
formula is C
10
H
11
N
4
NaO
5
S
and the molecular weight is 322.3.
The chemical structure of tazobactam sodium is:
4.
CLINICAL PARTICULARS
4.1
INDICATIONS
Piperacillin/tazobactam is indicated for the