DEXAMETHASONE injection, solution

Nchi: Marekani

Lugha: Kiingereza

Chanzo: NLM (National Library of Medicine)

Viambatanisho vya kazi:

DEXAMETHASONE (UNII: 7S5I7G3JQL) (DEXAMETHASONE - UNII:7S5I7G3JQL)

Inapatikana kutoka:

Vedco, Inc.

INN (Jina la Kimataifa):

DEXAMETHASONE

Tungo:

DEXAMETHASONE 2 mg in 1 mL

Njia ya uendeshaji:

INTRAMUSCULAR

Dawa ya aina:

PRESCRIPTION

Matibabu dalili:

DEXAMETHASONE INJECTION 2 mg/mL is indcated for  the treatment of primary bovine ketosis an as an anti-inflammatory agent in the bovine and equine. As supportive therapy, DEXAMETHASONE INJECTION 2 mg/mL may be used in the management of vairious rheumatic, allergic dermatologic, and other diseases known to be responsive to anti-inflammatory corticosteroids.  DEXAMETHASONE INJECTION 2 mg/mL may be used intravenously as supportive therapy when an immeidate hormonal response is required. Bovine Ketosis DEXAMETHASONE INJECTION 2 mg/mL is offered for the treatment of primary ktosis.  The gluconeogenic effects of DEXAMETHASONE INJECTION 2 mg/mL, when administered intramuscularyly, are generally noted within the first 5 to 12 hours.  When DEXAMETHASONE INJECTION 2 mg/mL is used intravenously, the effects may be noted sooner.  Blood sugar levels rise to normal levels repidly and genreally rise to above normal levels within 12 to 24 hours.  Acetone bodies are reduce to normal concentrations usually witnin 24 hours.  Th

Bidhaa muhtasari:

DEXAMETHASONE INJECTION 2 mg/mL, 100 mL multiple dose vials. Each mL contains :  2 mg dexamethasone; 500 mg polyethylene glycol 400; 9 mg benzyl alcohol, 1.8 mg methylparaben, and 0.2 mg propylparaben as preservatives; 4.75% alcohol; HCl to adjust pH to approximately 4.9; water for injection qs. TAKE TIME OBSERVE LABEL DIRECTIONS

Idhini hali ya:

Abbreviated New Animal Drug Application

Tabia za bidhaa

DEXAMETHASONE - DEXAMETHASONE INJECTION, SOLUTION
VEDCO, INC.
----------
DEXAMETHASONE INJECTION 2 MG/ML
SOLUTION FOR INTRAVENOUS OR INTRAMUSCULAR INJECTION
VETERINARY
CAUTIONFederal Law restricts this drug to use by or on the order of a
licensed veterinarian.
DESCRIPTION
DEXAMETHASONE INJECTION 2 mg/mL is a synthetic analogue of
prednisolone, having similar but
more potent anti-inflammatory therapeutic action and diversified
hormonal and metabolic effects.
Modification of the basic corticoid structure as achieved in
DEXAMETHASONE INJECTION 2
mg/mL offers enhanced anti-inflammatory effect compared to older
corticosteroids. The dosage of
DEXAMETHASONE INJECTION 2 mg/mL required is markedly lower than that
of prednisone and
prednisolone.
DEXAMETHASONE INJECTION 2 mg/mL is not species-specific; however, the
veterinarian should
read the sections on INDICATIONS, DOSAGE, SIDE EFFECTS,
CONTRAINDICATIONS,
PRECAUTIONS, and WARNINGS before this drug is used.
DEXAMETHASONE INJECTION 2 mg/mL is intended for _intravenous or
intramuscular_ administration.
Each mL contains 2 mg dexamethasone, 500 mg polyethylene glycol 400, 9
mg benzyl alcohol, 1.8 mg
methylparaben and 0.2 mg propylparaben as preservatives, 4.75%
alcohol, HCl to adjust pH to
approximately 4.9, water for injection q.s.
EXPERIMENTAL STUDIES
Experimental animal studies on dexamethasone have revealed it
possesses greater anti-inflammatory
activity than many steroids. Veterinary clinical evidence indicates
dexamethasone has approximately
twenty times the anti-inflammatory activity of prednisolone and
seventy to eighty times that of
hydrocortisone. Thymus involution studies show dexamethasone possesses
twenty-five times the
activity of prednisolone. In reference to mineralocorticoid activity,
dexamethasone does not cause
significant sodium or water retention. Metabolic balance studies show
that animals on controlled and
limited protein intake will exhibit nitrogen losses on exceedingly
high dosages.
ADMINISTRATION AND DOSAGE
Therapy with DEXAMETHASONE INJECTION 2 mg/