Země: Spojené státy
Jazyk: angličtina
Zdroj: NLM (National Library of Medicine)
DEXAMETHASONE (UNII: 7S5I7G3JQL) (DEXAMETHASONE - UNII:7S5I7G3JQL)
Vedco, Inc.
DEXAMETHASONE
DEXAMETHASONE 2 mg in 1 mL
INTRAMUSCULAR
PRESCRIPTION
DEXAMETHASONE INJECTION 2 mg/mL is indcated for the treatment of primary bovine ketosis an as an anti-inflammatory agent in the bovine and equine. As supportive therapy, DEXAMETHASONE INJECTION 2 mg/mL may be used in the management of vairious rheumatic, allergic dermatologic, and other diseases known to be responsive to anti-inflammatory corticosteroids. DEXAMETHASONE INJECTION 2 mg/mL may be used intravenously as supportive therapy when an immeidate hormonal response is required. Bovine Ketosis DEXAMETHASONE INJECTION 2 mg/mL is offered for the treatment of primary ktosis. The gluconeogenic effects of DEXAMETHASONE INJECTION 2 mg/mL, when administered intramuscularyly, are generally noted within the first 5 to 12 hours. When DEXAMETHASONE INJECTION 2 mg/mL is used intravenously, the effects may be noted sooner. Blood sugar levels rise to normal levels repidly and genreally rise to above normal levels within 12 to 24 hours. Acetone bodies are reduce to normal concentrations usually witnin 24 hours. Th
DEXAMETHASONE INJECTION 2 mg/mL, 100 mL multiple dose vials. Each mL contains : 2 mg dexamethasone; 500 mg polyethylene glycol 400; 9 mg benzyl alcohol, 1.8 mg methylparaben, and 0.2 mg propylparaben as preservatives; 4.75% alcohol; HCl to adjust pH to approximately 4.9; water for injection qs. TAKE TIME OBSERVE LABEL DIRECTIONS
Abbreviated New Animal Drug Application
DEXAMETHASONE - DEXAMETHASONE INJECTION, SOLUTION VEDCO, INC. ---------- DEXAMETHASONE INJECTION 2 MG/ML SOLUTION FOR INTRAVENOUS OR INTRAMUSCULAR INJECTION VETERINARY CAUTIONFederal Law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION DEXAMETHASONE INJECTION 2 mg/mL is a synthetic analogue of prednisolone, having similar but more potent anti-inflammatory therapeutic action and diversified hormonal and metabolic effects. Modification of the basic corticoid structure as achieved in DEXAMETHASONE INJECTION 2 mg/mL offers enhanced anti-inflammatory effect compared to older corticosteroids. The dosage of DEXAMETHASONE INJECTION 2 mg/mL required is markedly lower than that of prednisone and prednisolone. DEXAMETHASONE INJECTION 2 mg/mL is not species-specific; however, the veterinarian should read the sections on INDICATIONS, DOSAGE, SIDE EFFECTS, CONTRAINDICATIONS, PRECAUTIONS, and WARNINGS before this drug is used. DEXAMETHASONE INJECTION 2 mg/mL is intended for _intravenous or intramuscular_ administration. Each mL contains 2 mg dexamethasone, 500 mg polyethylene glycol 400, 9 mg benzyl alcohol, 1.8 mg methylparaben and 0.2 mg propylparaben as preservatives, 4.75% alcohol, HCl to adjust pH to approximately 4.9, water for injection q.s. EXPERIMENTAL STUDIES Experimental animal studies on dexamethasone have revealed it possesses greater anti-inflammatory activity than many steroids. Veterinary clinical evidence indicates dexamethasone has approximately twenty times the anti-inflammatory activity of prednisolone and seventy to eighty times that of hydrocortisone. Thymus involution studies show dexamethasone possesses twenty-five times the activity of prednisolone. In reference to mineralocorticoid activity, dexamethasone does not cause significant sodium or water retention. Metabolic balance studies show that animals on controlled and limited protein intake will exhibit nitrogen losses on exceedingly high dosages. ADMINISTRATION AND DOSAGE Therapy with DEXAMETHASONE INJECTION 2 mg/ Přečtěte si celý dokument