WELLBUTRIN SR TABLETS 150 mg

Land: Singapore

Språk: engelska

Källa: HSA (Health Sciences Authority)

Aktiva substanser:

BUPROPION HCl

Tillgänglig från:

GLAXOSMITHKLINE PTE LTD

ATC-kod:

N06AX12

Dos:

150 mg

Läkemedelsform:

TABLET, FILM COATED

Sammansättning:

BUPROPION HCl 150 mg

Administreringssätt:

ORAL

Receptbelagda typ:

Prescription Only

Tillverkad av:

GlaxoSmithKline LLC d/b/a GlaxoSmithKline

Bemyndigande status:

ACTIVE

Tillstånd datum:

1999-06-16

Bipacksedel

WELLBUTRIN SR
TM

BUPROPION HYDROCHLORIDE 

QUALITATIVE AND QUANTITATIVE COMPOSITION 

_WELLBUTRIN SR_ is available as sustained-release, film-coated
tablet each containing 
150 mg of bupropion hydrochloride. 

INDICATIONS 

_WELLBUTRIN_ _SR _is indicated for the treatment of depressive
illnesses.  

DOSAGE AND ADMINISTRATION 
_ _
_WELLBUTRIN SR _tablets should be swallowed whole. The tablets
should not be cut, 
crushed or chewed as this may lead to an increased risk of adverse
effects including 
seizures. 

Studies suggest that exposure to bupropion may be increased when
sustained release 
bupropion tablets are taken with food (see _Pharmacokinetics_). 

USE IN ADULTS  

The maximum single dose of _WELLBUTRIN SR _is 150 mg. 
_ _
_WELLBUTRIN SR_ tablets should be taken twice daily with an interval
of at least 8 hours 
between successive doses. 

Insomnia is a very common adverse event which is often transient.
 Insomnia may be 
reduced by avoiding dosing at bedtime (provided there is at least 8
hours between doses) 
or, if clinically indicated, dose reduction 
may be considered.

Initial Treatment 
Dosing with _WELLBUTRIN SR_ Tablets should begin at 150 mg/day
given as a single 
daily dose in the morning. If the 150 mg initial dose is adequately
tolerated, patients who 
are not responding adequately may benefit from an increase to 300
mg/day, given as 150 
mg twice daily, after an interval of at least one week. There
should be an interval of at 
least 8 hours between successive doses. 

The maximum daily dose should not exceed 300 mg/day. 

Maintenance therapy 
It is generally agreed that acute episodes of depression require
6 months or longer of 
antidepressant drug treatment.   

USE IN CHILDREN AND ADOLESCENTS 
_ _
_WELLBUTRIN SR_ is not indicated for use in children or adolescents
aged less than 18 
years (see _Warnings and Precautions_). The safety and efficacy
of _WELLBUTRIN_ _SR _
tablets in patients unde

Produktens egenskaper

WELLBUTRIN SR
BUPROPION HYDROCHLORIDE
QUALITATIVE AND QUANTITATIVE COMPOSITION
_WELLBUTRIN SR_ is available as sustained-release, film-coated tablet
each containing
150 mg of bupropion hydrochloride.
CLINICAL INFORMATION
INDICATIONS
_WELLBUTRIN_ _SR _is indicated for the treatment of major depressive
episodes.
DOSAGE AND ADMINISTRATION
_ _
Pharmaceutical form: Sustained-release (SR) film-coated tablet.
_ _
_WELLBUTRIN SR _tablets should be swallowed whole. The tablets should
not be cut,
crushed or chewed as this may lead to an increased risk of adverse
effects including
seizures.
Studies suggest that exposure to bupropion may be increased when
sustained-release
bupropion tablets are taken with food (see _Pharmacokinetics_).
USE IN ADULTS
The maximum single dose of _WELLBUTRIN SR _is 150 mg.
_ _
_WELLBUTRIN SR_ tablets should be taken twice daily with an interval
of at least
eight hours between successive doses.
Insomnia is a very common adverse event which is often transient.
Insomnia may be
reduced by avoiding dosing at bedtime (provided there is at least
eight hours between
doses) or, if clinically indicated, dose reduction may be considered
.
Initial treatment
Dosing with _WELLBUTRIN SR_ tablets should begin at 150 mg/day given
as a single daily
dose in the morning. If the 150 mg initial dose is adequately
tolerated, patients who are
not responding adequately may benefit from an increase to 300 mg/day,
given as 150 mg
twice daily, after an interval of at least one week. There should be
an interval of at least
eight hours between successive doses.
The maximum daily dose should not exceed 300 mg/day.
Maintenance therapy
It is generally agreed that acute episodes of depression require 6
months or longer of
antidepressant drug treatment.
USE IN CHILDREN AND ADOLESCENTS
_ _
_WELLBUTRIN SR_ is not indicated for use in children or adolescents
aged less than 18
years (see _Warnings and Precautions_). The safety and efficacy of
_WELLBUTRIN_ _SR _
tablets in patients under 18 years of age have not been established.
USE