TIA- tiamulin hydrogen fumarate solution, concentrate

Land: USA

Språk: engelska

Källa: NLM (National Library of Medicine)

Aktiva substanser:

TIAMULIN FUMARATE (UNII: ION1Q02ZCX) (TIAMULIN - UNII:E38WZ4U54R)

Tillgänglig från:

Virbac AH, Inc.

Administreringssätt:

ORAL

Receptbelagda typ:

OTC

Terapeutiska indikationer:

TIA 12.5% (tiamulin hydrogen fumarate), when administered in the drinking water for five consecutive days, is an effective antibiotic for the treatment of swine dysentery associated with Brachyspira (formerly Serpulina or Treponema ) hyodysenteriae susceptible to tiamulin at a dose level of 3.5 mg tiamulin hydrogen fumarate per pound of body weight daily and for treatment of swine pneumonia due to Actinobacillus pleuropneumoniae susceptible to tiamulin when given at 10.5 mg tiamulin hydrogen fumarate per pound of body weight daily. Swine being treated with TIA 12.5% (tiamulin hydrogen fumarate) should not have access to feeds containing polyether ionophores (e.g. monensin, lasalocid, narasin, salinomycin and semduramicin) as adverse reactions may occur.

Bemyndigande status:

Abbreviated New Animal Drug Application

Produktens egenskaper

TIA- TIAMULIN HYDROGEN FUMARATE SOLUTION, CONCENTRATE
VIRBAC AH, INC.
----------
TIA™ 12.5%
(TIAMULIN HYDROGEN FUMARATE)
DESCRIPTION
TIA 12.5% (tiamulin hydrogen fumarate) Liquid Concentrate is a
solution containing
12.5% tiamulin hydrogen fumarate (w/v) in an aqueous solution.
The active ingredient, tiamulin hydrogen fumarate, chemically is
14-desoxy-14-[(2-
diethylaminoethyl) mercaptoacetoxy] mutilin hydrogen fumarate, a
semi-synthetic
diterpene antibiotic. TIA 12.5% Liquid Concentrate is for use only in
preparing medicated
drinking water for swine.
ACTIONS
Tiamulin is active against _Brachyspira_ (formerly _Serpulina _or_
Treponema) hyodysenteriae_
and_ Actinobacillus pleuropneumoniae_. It is readily absorbed from the
gut and can be
found in the blood within 30 minutes after dosing.
INDICATIONS
TIA 12.5% (tiamulin hydrogen fumarate), when administered in the
drinking water for
five consecutive days, is an effective antibiotic for the treatment of
swine dysentery
associated with _Brachyspira_ (formerly _Serpulina _or_ Treponema_)_
hyodysenteriae_
susceptible to tiamulin at a dose level of 3.5 mg tiamulin hydrogen
fumarate per pound
of body weight daily and for treatment of swine pneumonia due to
_Actinobacillus_
_pleuropneumoniae_ susceptible to tiamulin when given at 10.5 mg
tiamulin hydrogen
fumarate per pound of body weight daily.
CONTRAINDICATIONS
Swine being treated with TIA 12.5% (tiamulin hydrogen fumarate) should
not have
access to feeds containing
polyether ionophores (e.g. monensin, lasalocid, narasin, salinomycin
and semduramicin)
as adverse reactions may occur.
WARNING: Keep out of reach of children. Avoid contact with skin.
Direct contact with
skin or mucous membranes may cause irritation.
RESIDUE WARNINGS: Withdraw medicated water 3 days before slaughter
after
treatment at 3.5 mg per pound body weight and 7 days before slaughter
after
treatment at 10.5 mg per pound body weight.
CAUTION: FOR USE IN DRINKING WATER OF SWINE ONLY - NOT FOR USE IN
HUMANS.
Prepare fresh medicated water daily. Use as t