Land: Singapore
Språk: engelska
Källa: HSA (Health Sciences Authority)
DESLORATADINE
ORGANON SINGAPORE PTE. LTD.
R06AX27
5 mg
TABLET, FILM COATED
DESLORATADINE 5 mg
ORAL
Pharmacy Only
Organon Heist bv
ACTIVE
2001-12-26
AERIUS® Tablets Brand of desloratadine Read this leaflet carefully before you start taking this medicine because it contains important information for you. This medicine is available without a prescription. However, you will still need to take Aerius Tablets carefully to get the best results from it. - Keep this leaflet. You may need to read it again. - This medicine is available without a prescription. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours. - If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. In this leaflet: 1. What Aerius is and what it is used for 2. Before you take Aerius 3. How to take Aerius 4. Possible side effects 5. How to store Aerius 6. Further information 1. WHAT AERIUS IS AND WHAT IT IS USED FOR Aerius is an antiallergy medicine that does not make you drowsy. It helps control your allergic reaction and its symptoms. Aerius relieves symptoms associated with allergic rhinitis (inflammation of the nasal passages caused by an allergy, for example, hay fever or allergy to dust mites). These symptoms include sneezing, runny, stuffy or itchy nose, itchy palate, itchy, red or watery eyes and coughing. Aerius is also used to relieve the symptoms associated with urticaria (a skin condition caused by an allergy). These symptoms include itching and hives. Relief of these symptoms lasts a full day and helps you to resume your normal daily activities and sleep. 2. BEFORE YOU TAKE AERIUS Do not take Aerius - if you are allergic (hypersensitive) to desloratadine, to any of the other ingredients of Aerius or to loratadine. Aerius is indicated for adults and adolescents (12 years of age and older). Taking other medicines There are no known interactions of Aerius with other medicines. Taking Aerius with food and drink Aerius may be taken with or without a meal. Pregnancy and breast-feeding Ask your doctor or pharmacist for advice before taking any medicine during pregnancy a Läs hela dokumentet
S-CCDS-MK4117-MTL-112017 AERIUS® Tablets Brand of desloratadine DESCRIPTION: Each AERIUS Tablet contains 5.0 mg of desloratadine. AERIUS Tablet is a light blue round tablet, embossed with elongated letters ‘S’ and ‘P’ on one side and plain on the other. Inactive Ingredients: dibasic calcium phosphate dihydrate, microcrystalline cellulose, corn starch, talc, film coat [containing lactose monohydrate, hypromellose, titanium dioxide, macrogol 400, indigotin (E132)], clear coat (containing hypromellose, macrogol 400), carnauba wax, and white wax. ACTIONS: Desloratadine is a non-sedating long-acting histamine antagonist with potent, selective peripheral H 1 -receptor antagonist activity. Desloratadine has demonstrated antiallergic, antihistaminic, and anti-inflammatory activity. In addition to antihistaminic activity, desloratadine has demonstrated antiallergic and anti-inflammatory activity from numerous in vitro (mainly conducted on cells of human origin) and in vivo studies. These studies have shown that desloratadine inhibits the broad cascade of events that initiate and propagate allergic inflammation, including, the release of proinflammatory cytokines including IL-4, IL-6, IL-8, IL-13, the release of important proinflammatory chemokines such as RANTES (Regulated upon Activation, Normal T-cell Expressed and Secreted), superoxide anion production by activated polymorphonuclear neutrophils, eosinophil adhesion and chemotaxis, the expression of the adhesion molecules such as P-selectin, IgE-dependent release of histamine, prostaglandin (PGD2), and leukotriene (LTC4), the acute allergic bronchoconstrictor response and allergic cough in animal models. PRECLINICAL TOXICOLOGY: Desloratadine is the primary active metabolite of loratadine. Non-clinical studies conducted with desloratadine and loratadine demonstrated comparable qualitative and quantitative toxicity profile of desloratadine and loratadine at comparable levels of exposure to desloratadine. Carcinogenesis, Mutagenesis, Im Läs hela dokumentet