Land: Malaysia
Språk: engelska
Källa: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Acetylcysteine
HEALOL PHARMACEUTICALS SDN. BHD.
Acetylcysteine
30 Sachets; 50 Sachets
XL Laboratories Pvt. Ltd.
ACEVIZ _Consumer Medication Information Leaflet (RiMUP)_ Acetylcysteine Powder for Oral Solution 200 mg 1 WHAT IS IN THIS LEAFLET 1. What ACEVIZ is used for 2. How ACEVIZ works 3. Before you use ACEVIZ 4. How to use ACEVIZ 5. While you are using it 6. Side effects 7. Storage and Disposal of ACEVIZ 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision 11. Serial number WHAT IS ACEVIZ USED FOR ACEVIZ is indicated for all respiratory tract diseases leading to the formation of thick secretions difficult to be expectorated, such as acute and chronic bronchitis, laryngitis, sinusitis, tracheitis, influenza, bronchial asthma and (as complementary treatment) mucoviscidosis. HOW ACEVIZ WORKS Each sachet contains the active substance acetylcysteine. Acetylcysteine belongs to a group of medicines called mucolytics which work by thinning the mucus (phlegm) so that it can be coughed up more easily. BEFORE YOU USE ACEVIZ - _When you must not use it _ Do not take ACEVIZ if: • you are allergic to the ingredients of this product • you are pregnant; trying to get pregnant or think you may be pregnant. • you are breast-feeding. - _Before you start to use it _ Ask your doctor or pharmacist for advice before taking any medicine. Please make sure you have understood the explanation given by your doctor or pharmacist before taking this medicine. Speak to your doctor /pharmacist if you have any other health related problems. - _Taking other medications _ Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop. Tell your doctor if you are taking the following medicines before starting ACEVIZ: • medicines to treat coughs (e.g. cough syrup) • activated charcoal, used to treat poisoning • drugs used to treat bacterial infections, antibiotics (e.g. cefalexin, cefuroxime, cefadroxil, cefaclor, ceftriaxone) • medicines to treat angina attacks, (tightness in your chest, neck and arm) (e.g. glycer Läs hela dokumentet
Size : 165x120 mm Manufactured by : XL LABORATORIES PVT. LTD. E-1223, Phase-I Extn., (Ghatal) RIICO Indl. Area, Bhiwadi-301019, Rajasthan, India Product Registration Holder: HEALOL PHARMACEUTICALS SDN.BHD 74-3, Jalan Wangsa Delima 6, KLSC Wangsa Maju, 53300 Kuala Lumpur, Malaysia. ACEVIZ Acetylcysteine Powder for Oral Solution 200 mg PRODUCT NAME ACEVIZ (Acetylcysteine Powder for Oral Solution 200 mg) NAME AND STRENGTH OF ACTIVE SUBSTANCE(S) Acetylcysteine 200 mg PRODUCT DESCRIPTION White to off-white, granular powder after reconstitution in warm water forms a clear solution. PHARMACODYNAMICS & PHARMACOKINETICS _Pharmacodynamics_ Pharmacotherapeutic group: Mycolytics, ATC code: R05CB01 N-acetyl-L-cysteine (NAC), the active ingredient in Acetylcysteine 200 mg Powder for Oral Solution exerts an intense mucolytic-fluidizing action on mucous and mucopurulent secretions by depolymerizing the mucoproteic complexes and the nucleic acids which confer viscosity to the vitreous and purulent component of the sputum and other secretions. Furthermore, acetylcysteine exerts a direct antioxidant action, having a free thiol (- SH) nucleophilic group that is able to interact directly with electrophilic groups of oxidant radicals. Of particular interest is the recent finding that acetylcysteine protects α1- antitrypsin enzyme inhibiting elastase from inactivation by hypochlorous acid (HOCl), a powerful oxidant agent produced by the myeloperoxidase enzyme of activated phagocytes. Due to its molecular structure, acetylcysteine can readily cross cell membranes. Inside the cell, NAC is deacetylated to L-cysteine, an amino acid essential for glutathione synthesis (GSH). GSH is a highly reactive tripeptide found ubiquitously in the various tissues of animals and is essential for the maintenance of functional capacity as well as cellular morphological integrity. It is the most important protective intracellular mechanism against oxidant radicals, both exogenous and endogenous, as well as toward numerous cytotoxic substances. These featu Läs hela dokumentet