Ceftazidime Alphapharm

Country: Аустралија

Језик: Енглески

Извор: Department of Health (Therapeutic Goods Administration)

Активни састојак:

Ceftazidime pentahydrate

Доступно од:

Alphapharm Pty Ltd

Класа:

Medicine Registered

Информативни летак

CEFTAZIDIME
ALPHAPHARM

_contains the active ingredient ceftazidime (as pentahydrate)_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET?
This leaflet answers some common
questions about CEFTAZIDIME
Alphapharm.
It does not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
All medicines have benefits and
risks. Your doctor has weighed the
risks of you being given
CEFTAZIDIME Alphapharm against
the benefits expected for you.
IF YOU HAVE ANY CONCERNS ABOUT
BEING GIVEN THIS MEDICINE, TALK TO
YOUR DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH YOUR
MEDICINE.
You may need to read it again.
WHAT CEFTAZIDIME
ALPHAPHARM IS USED
FOR?
CEFTAZIDIME Alphapharm is used
to treat a wide range of infections
caused by bacteria. These infections
may affect the chest (bronchitis or
pneumonia), ears, nose, throat,
bladder and urinary tract, skin and
soft tissue, stomach or bones.
This medicine belongs to a group of
medicines called cephalosporins.
It works by killing the bacteria that
cause these infections.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY THIS MEDICINE
HAS BEEN PRESCRIBED FOR YOU.
Your doctor may have prescribed it
for another reason.
CEFTAZIDIME Alphapharm is
available only with a doctor's
prescription.
CEFTAZIDIME Alphapharm is not
addictive.
BEFORE YOU ARE GIVEN
CEFTAZIDIME
ALPHAPHARM
_WHEN YOU MUST NOT BE GIVEN_
_IT_
YOU MUST NOT BE GIVEN
CEFTAZIDIME ALPHAPHARM IF
YOU HAVE EVER HAD AN ALLERGIC
REACTION TO:
•
any medicine containing
cephalosporins or penicillins
•
any of the ingredients listed at the
end of this leaflet.
Some of the symptoms of an allergic
reaction may include shortness of
breath; wheezing or difficulty
breathing; swelling of the face, lips,
tongue or other parts of the body;
rash, itching or hives on the skin.
YOU MUST NOT BE GIVEN THIS
MEDICINE AFTER THE EXPIRY DATE
PRINTED ON THE PACK OR IF THE
PACKAGING IS TORN OR SHOWS SIGNS OF
TAMPERING.
IF YOU ARE NOT SURE WHETHER YOU
SHOULD BE GIVEN THIS MEDICINE, TALK
TO YOUR

Карактеристике производа

CEFTAZIDIME 
ALPHAPHARM 
_Ceftazidime pentahydrate _

PRODUCT INFORMATION 
NAME OF THE MEDICINE 
Active ingredient: 
ceftazidime pentahydrate 
Chemical name: 
(6_R_,7_R_)-7-[[(_Z_)-2-(2-aminothiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino] 
acetyl] amino]8-oxo-3-[(1-pyridinio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-
carboxylate pentahydrate. 
Structural formula: 

Molecular formula: 
C
22
H
22
N
6
O
7
S
2
,5H
2
O 

Molecular weight: 
637 

CAS Registry no.: 
78439-06-2 
DESCRIPTION 
Ceftazidime  pentahydrate  is  a  white  or  almost  white,  crystalline  powder,  slightly  soluble  in  water  and  in 
methanol, practically insoluble in acetone and in alcohol.
 It dissolves in acid and alkali solutions.  
Ceftazidime  Alphapharm  is  supplied  in  vials  containing  1  g  and  2  g  of  ceftazidime  (as  pentahydrate)  with 
sodium carbonate anhydrous (116.4 mg per gram of  ceftazidime).  On the addition of water for injections, 
Ceftazidime Alphapharm dissolves with effervescence to produce
a solution for injection.  
Ceftazidime Alphapharm contains approximately 54 mg (2.3 mEq)
of sodium per gram of ceftazidime.  
116.4 mg ceftazidime pentahydrate is equivalent to
100 mg ceftazidime free acid.    
PHARMACOLOGY

PHARMACOKINETICS 
Absorption  of  ceftazidime  after  oral  administration  is  negligible;  therefore,  Ceftazidime  Alphapharm  is 
CEFTAZIDIME ALPHAPHARM 
– Product Information

2 

intended for parenteral use only. 
In man after a single intramuscular administration of 500 mg and 1 g, mean peak serum levels of 18 and 37 
mg/L  respectively  are  achieved  at  1  hour  falling  to  8  and  2  mg/L  and  20  and  5  mg/L  at  4  and  8  hours 
respectively  for  the  two  doses.    Five  minutes after�