Kraj: Australia
Język: angielski
Źródło: Department of Health (Therapeutic Goods Administration)
Ceftazidime pentahydrate
Alphapharm Pty Ltd
Medicine Registered
CEFTAZIDIME ALPHAPHARM _contains the active ingredient ceftazidime (as pentahydrate)_ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET? This leaflet answers some common questions about CEFTAZIDIME Alphapharm. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have benefits and risks. Your doctor has weighed the risks of you being given CEFTAZIDIME Alphapharm against the benefits expected for you. IF YOU HAVE ANY CONCERNS ABOUT BEING GIVEN THIS MEDICINE, TALK TO YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH YOUR MEDICINE. You may need to read it again. WHAT CEFTAZIDIME ALPHAPHARM IS USED FOR? CEFTAZIDIME Alphapharm is used to treat a wide range of infections caused by bacteria. These infections may affect the chest (bronchitis or pneumonia), ears, nose, throat, bladder and urinary tract, skin and soft tissue, stomach or bones. This medicine belongs to a group of medicines called cephalosporins. It works by killing the bacteria that cause these infections. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY THIS MEDICINE HAS BEEN PRESCRIBED FOR YOU. Your doctor may have prescribed it for another reason. CEFTAZIDIME Alphapharm is available only with a doctor's prescription. CEFTAZIDIME Alphapharm is not addictive. BEFORE YOU ARE GIVEN CEFTAZIDIME ALPHAPHARM _WHEN YOU MUST NOT BE GIVEN_ _IT_ YOU MUST NOT BE GIVEN CEFTAZIDIME ALPHAPHARM IF YOU HAVE EVER HAD AN ALLERGIC REACTION TO: • any medicine containing cephalosporins or penicillins • any of the ingredients listed at the end of this leaflet. Some of the symptoms of an allergic reaction may include shortness of breath; wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hives on the skin. YOU MUST NOT BE GIVEN THIS MEDICINE AFTER THE EXPIRY DATE PRINTED ON THE PACK OR IF THE PACKAGING IS TORN OR SHOWS SIGNS OF TAMPERING. IF YOU ARE NOT SURE WHETHER YOU SHOULD BE GIVEN THIS MEDICINE, TALK TO YOUR Przeczytaj cały dokument
CEFTAZIDIME ALPHAPHARM _Ceftazidime pentahydrate _ PRODUCT INFORMATION NAME OF THE MEDICINE Active ingredient: ceftazidime pentahydrate Chemical name: (6_R_,7_R_)-7-[[(_Z_)-2-(2-aminothiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino] acetyl] amino]8-oxo-3-[(1-pyridinio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2- carboxylate pentahydrate. Structural formula: Molecular formula: C 22 H 22 N 6 O 7 S 2 ,5H 2 O Molecular weight: 637 CAS Registry no.: 78439-06-2 DESCRIPTION Ceftazidime pentahydrate is a white or almost white, crystalline powder, slightly soluble in water and in methanol, practically insoluble in acetone and in alcohol. It dissolves in acid and alkali solutions. Ceftazidime Alphapharm is supplied in vials containing 1 g and 2 g of ceftazidime (as pentahydrate) with sodium carbonate anhydrous (116.4 mg per gram of ceftazidime). On the addition of water for injections, Ceftazidime Alphapharm dissolves with effervescence to produce a solution for injection. Ceftazidime Alphapharm contains approximately 54 mg (2.3 mEq) of sodium per gram of ceftazidime. 116.4 mg ceftazidime pentahydrate is equivalent to 100 mg ceftazidime free acid. PHARMACOLOGY PHARMACOKINETICS Absorption of ceftazidime after oral administration is negligible; therefore, Ceftazidime Alphapharm is CEFTAZIDIME ALPHAPHARM – Product Information 2 intended for parenteral use only. In man after a single intramuscular administration of 500 mg and 1 g, mean peak serum levels of 18 and 37 mg/L respectively are achieved at 1 hour falling to 8 and 2 mg/L and 20 and 5 mg/L at 4 and 8 hours respectively for the two doses. Five minutes after Przeczytaj cały dokument