Baytril Flavour Tablets 50 mg

Država: Malezija

Jezik: angleščina

Source: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktivna sestavina:

ENROFLOXACIN

Dostopno od:

ELANCO MALAYSIA SDN BHD

INN (mednarodno ime):

ENROFLOXACIN

Enote v paketu:

50.00 mcg/mL

Izdeluje:

KVP Pharma + Veterinar Produkte GmbH

Lastnosti izdelka

M0004436
Mock-Up / 500668MB
148 x 210 mm
8 pt
MK
2
23.03.2021
Schwarz
Kontur
For Dogs and Cats
50 MG
TABLETS
Antimicrobial
M0004436
PRODUCT DESCRIPTION
BAYTRIL
® FLAVOUR TABLETS 50 MG is a light brown to
brown, slightly marbled, round and voulted tablet.
Each tablet contains 50 mg of enrofloxacin.
PHARMACODYNAMICS
Enrofloxacin is bactericidal in action with activity
against Gram positive and Gram negative bacteria
and mycoplasmas. The mechanism of action of
the quinolones is unique among antimicrobials –
they act primarily to inhibit bacterial DNA gyrase,
an enzyme responsible for controlling the super
-
coiling of bacterial DNA during replication.
Resealing of the double standard helix is inhibited
resulting in irreversible degradation of the
chromosomal DNA. The fluoroquinolones also
possess activity against bacteria in the stationary
phase by an alteration of the permeability of the
outer membrane phospholipid cell wall.
PHARMACOKINETICS
The pharmacokinetics of enrofloxacin in dogs and
cats are such that oral and parenteral administra
-
tion leads to similar serum levels. Enrofloxacin
possesses a high distribution volume. Tissue
levels 2 – 3 times higher than that found in the
serum, have been demonstrated in laboratory
animals and target species. Organs in which high
levels can be expected are the lungs, liver, kidney,
skin, bone and lymphatic system. Enrofloxacin
also distributes into the cerebrospinal fluid, the
aqueous humour and the foetus in pregnant
animals.
INDICATION
The product is for use in cats and dogs in the
treatment of bacterial infections of the alimentary,
respiratory and urogenital tracts, skin, secondary
wound infections and otitis externa where clinical
experience, supported where possible by sensi
-
tivity testing of the causal organism, indicates
enrofloxacin as the drug of choice.
RECOMMENDED DOSAGE
1 tablet Baytril Flavour Tablets 50 mg per 10 kg
bodyweight
MODE OF ADMINISTRATION
The dosage rate of enrofloxacin is 5 mg/kg given
orally once daily or as a divided dose twice daily
fo