REGUMATE- altrenogest solution

Krajina: Spojené štáty

Jazyk: angličtina

Zdroj: NLM (National Library of Medicine)

Aktívna zložka:

altrenogest (UNII: 2U0X0JA2NB) (altrenogest - UNII:2U0X0JA2NB)

Dostupné z:

Merck Sharp & Dohme Corp.

INN (Medzinárodný Name):

altrenogest

Zloženie:

altrenogest 2.2 mg in 1 mL

Spôsob podávania:

ORAL

Typ predpisu:

PRESCRIPTION

Terapeutické indikácie:

INDICATIONS: For suppression of estrus in mares. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. This facilitates the attainment of regular cyclicity during the transition from winter anestrus to the physiological breeding season. Suppression of estrus will also facilitate management of prolonged estrus conditions. Suppression of estrus may be used to facilitate scheduled breeding during the physiological breeding season. CONTRAINDICATIONS: Do not use Regu-Mate® (altrenogest) in mares having a previous or current history of uterine inflammation (e.g., acute, subacute, or chronic endometritis). Natural or synthetic gestagen therapy may exacerbate existing low-grade or "smoldering" uterine inflammation into a fulminating uterine infection in some instances.

Prehľad produktov:

HOW SUPPLIED: Regu-Mate® (altrenogest) contains 2.2 mg/mL in an oil solution. Product supplied in 1,000 mL plastic bottles. Regu-Mate® Equine Dosing Device supplied separately.

Stav Autorizácia:

New Animal Drug Application

Súhrn charakteristických

REGUMATE- ALTRENOGEST SOLUTION
MERCK SHARP & DOHME CORP.
----------
REGU-MATE (ALTRENOGEST)
2.2 mg altrenogest per mL (0.22%)
Oral Solution for Horses
CAUTION:
FEDERAL LAW RESTRICTS THIS DRUG TO USE BY OR ON THE ORDER OF A
LICENSED
VETERINARIAN.
DESCRIPTION:
Regu-Mate (altrenogest) contains the active synthetic progestin,
altrenogest. The
chemical name is 17a-allyl-17b-hydroxyestra-4,9,11-trien-3-one. The
CAS Registry
Number is 850-52-2. The chemical structure is:
Each mL of Regu-Mate (altrenogest) contains 2.2 mg of altrenogest in
an oil solution.
Regu-Mate (altrenogest) produces a progestational effect in mares.
INDICATIONS:
For suppression of estrus in mares. Suppression of estrus allows for a
predictable
occurrence of estrus following drug withdrawal. This facilitates the
attainment of regular
cyclicity during the transition from winter anestrus to the
physiological breeding season.
Suppression of estrus will also facilitate management of prolonged
estrus conditions.
Suppression of estrus may be used to facilitate scheduled breeding
during the
physiological breeding season.
DOSAGE AND ADMINISTRATION:
Administer solution orally at the rate of 1 mL per 110 pounds body
weight (0.044
mg/kg) once daily for 15 consecutive days. Administer solution
directly on the base of
the mare's tongue or on the mare's usual grain ration.
DOSAGE CHART
APPROXIMATE WEIGHT
DOSE IN
®
®
®
®
(POUNDS)
ML
770
7
880
8
990
9
1100
10
1210
11
1320
12
When handling Regu-Mate product, the dosing device, or syringes,
ALWAYS USE VINYL,
NEOPRENE, OR NITRILE GLOVES. LATEX GLOVES ARE NOT PROTECTIVE. The
product may
be dosed using Regu-Mate Equine Dosing Device or a luer lock syringe.
Use of the
Regu-Mate Equine Dosing Device is recommended to reduce the risk of
human
exposure. Follow all instructions when using the dosing device. DO NOT
USE ANY
DOSING DEVICE OTHER THAN THE REGU-MATE EQUINE DOSING DEVICE.
FOR USE WITH REGU-MATE EQUINE DOSING DEVICE, first assemble the device
according to directions supplied with the Regu-Mate Equine Dosing
Devi