LICONATE TABLET 300MG

Krajina: Malajzia

Jazyk: angličtina

Zdroj: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Aktívna zložka:

LITHIUM CARBONATE

Dostupné z:

MALAYSIAN PHARMACEUTICAL INDUSTRIES SDN. BHD.

INN (Medzinárodný Name):

LITHIUM CARBONATE

Počet v balení:

1000 Tablets

Výrobca:

MALAYSIAN PHARMACEUTICAL INDUSTRIES SDN. BHD.

Príbalový leták

_Consumer Medication Information Leaflet (RiMUP) _
1
LICONATE TABLET
Lithium Carbonate (300mg)
WHAT IS IN THIS LEAFLET:
1.
What Liconate Tablet is used for
2.
How Liconate Tablet works
3.
Before you use Liconate Tablet
4.
How to use Liconate Tablet
5.
While you are using Liconate Tablet
6.
Side Effects
7.
Storage
and
Disposal
of
Liconate
Tablet
8.
Product description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of Revision
WHAT LICONATE TABLET IS USED FOR
Lithium
Carbonate
is
the
active
ingredient
of
Liconate
Tablet.
It
is
indicated
for
the
prophylaxis
and
treatment of hypomania (a less severe
form
of
mania)
or
mania
(excitement
manifested
by
mental
and
physical
hyperactivity,
disorganization
of
behavior, and elevation of mood), in the
prophylaxis of manic depression (bipolar
illness
or
bipolar
depression)
and
recurrent depression (unipolar illness or
unipolar depression).
HOW LICONATE TABLET WORKS?
The mechanism of anti-manic effects is
unknown;
lithium
ions
may
act
by
competing with sodium ions at various
sites in the body.
BEFORE YOU USE LICONATE TABLET
_- When you must not use it _

If you have severe kidney disease,
debilitated
or
dehydrated
and
sodium depeletion.

If you have cardiovascular disease
and hypothyroidism (a condition in
which
the
body
lacks
sufficient
thyroid hormone) and also Addison
Disease
(a
disorder
that
occurs
when
the
adrenal
glands
do
not
produce enough hormones).

If
you or your child is under 12
years of age.

If you are taking diuretic medicines.

If
you
have
hypersensitivity
(allergic) to lithium carbonate or its
ingredient.
_- Before you start to use it _
You must tell your doctor if:

you have allergies to any medicine
which you have usen previously to
treat your current condition.

you are pregnant, trying to become
pregnant or breast-feeding. Do not
take Liconate Tablet until you and
your doctor have discussed the risks
and benefits involved.
_- Taking other medicines _
Always
inform
your
doctor
and
pharmacist if you are taking any other
medicine

Súhrn charakteristických

7038-05
LICONATE TABLETS 300MG
NAME AND STRENGTH OF ACTIVE INGREDIENT(S):
Each tablet contains:
Lithium Carbonate
…………………………………………………300mg
PRODUCT DESCRIPTION:
A white, flat of diameter 11mm round tablet with ‘MPI’ logo.
PHARMACODYNAMICS
:
Lithium possesses anti-manic effects but the mechanism is unknown;
lithium ions may act by competing with sodium ions at
various sites in the body.
PHARMACOKINETICS:
Lithium is readily and completely absorbed from the gastro-intestinal
tract when taken as one of its salts. Absorption can be
affected by the formulation of preparation taken. Peak serum
concentrations are obtained between 0.5 and 3 hours after ingestion
from conventional tablets. Lithium is distributed throughout the body
and distribution is complete within 6 to 10 hours; higher
concentration occur in the bones, the thyroid gland, and portions of
the brain, than in the serum. Lithium is excreted predominantly
in the urine; only a small amount can be detected in the faeces,
saliva and sweat. It is not bound to plasma proteins. It crosses the
placenta and is excreted in breast milk. In patients with normal renal
function the average elimination half-life is about 20 to 24
hours.
INDICATION:
It is used in the prophylaxis and treatment of mania or hypomania, in
the prophylaxis of manic depression (bipolar illness or
bipolar depression ) and recurrent depression (unipolar illness or
unipolar depression).
RECOMMENDED DOSAGE:
To be take orally. This medication may be taken with food, to minimize
stomach upset.
_Acute treatment of mania and hypomania : _
1.5 – 2g daily may be given in divided doses for the first 5 to 7
days, together with close checks on serum-lithium
concentrations, a higher concentration, often up to 1.5 mmol/L may be
required. The dose may need to be reduced rapidly
once the acute phase has passed.
_Prophylactic therapy : _
The usual dose is 0.5 – 1.2g daily in divided doses. During the
initial stages of lithium therapy, serum-lithium
concentration must be