Apo-Atenol tablets

Страна: Армения

Язык: английский

Источник: Դեղերի և բժշկական տեխնոլոգիաների փորձագիտական կենտրոնի գործունեության Հայաստանի Հանրապետությունում

Активный ингредиент:

atenolol

Доступна с:

Apotex Inc.

код АТС:

C07AB03

ИНН (Международная Имя):

atenolol

дозировка:

50mg

Фармацевтическая форма:

tablets

Штук в упаковке:

(30/3x10/) in blister, (100) in plastic container

Тип рецепта:

Prescription

Статус Авторизация:

Registered

Дата Авторизация:

2017-06-05

тонкая брошюра

READ THIS FOR SAFE
AND
EFFECTIVE USE OF YOUR
MEDICINE
PATIENT MEDICATION
INFORMATION
B
npo-nrE¡lot
atenolol tablets
Read
this
carefully before
you
start
taking
APO-ATENOL
and each
time
you
get
a
refill.
This leaflet
is a
summãry
and will
not
tell
you
everything
about this
drug.
Talk
to
your
healthcare
professional
about
your
medical condition
and treatment and ask
if
there
is
any
new
information
about APO-ATENOL.
What
is
APO-ATENOL
used
for?
APO-ATENOL
is
used
to
treat
high
blood
pressure
(also
known as hypertension)
in
adults.
lt
can
be used
alone or
with
other
medicines.
APCI-ATENOL
is
also used to
prevent
chest
pain
(also
known
as
angina) in
adults.
How
does
APO-ATENOL
work?
APO-ATENOL belongs to a
group
of
drugs
called
"beta
blockers".
lt
makes
your
heart
beat more slowly
and
less
forcefully. This medicine
does
not
cure
your
disease but helps
to
control
it
What
are
the
ingredients
in
APO-ATENOL?
Medicinal ingredients: atenolol
Non-medicinal
ingredients: colloidal silicon dioxide,
crospovidone, magnesium
stearate
and
microcrystalline
cellulose,
APO-ATENOL
comes
in
the
following
dosage forms:
Tablets:
50
mg and
100
mg
Do not
:-i
use
APO-ATENOL
if
you:
are
allergic
to
atenolol or any
of
the ingredients
in
APO-ATENOL.
have
slow or
irregular heartbeats
or
if
you
have
been told that
you
have
heart
block.
have severe heart damage and
your
heart
is not
able to
pump
enough
blood
to
meet
your
body's
needs.
have
heart
failure and
you
notice
that
your
symptoms
are
getting
worse.
For
example
you
feel
more
tired, are out of breath
more often,
or
have
swelling
of
the
ankles.
have a
problem
with
your
heart's electrical
conduction
(that
causes
you
to
have
chest
pain,
difficulty
breathing, nausea, fatigue
and
fainting).
have
low
blood
pressure.
have
serious
problems
with
blood
flow
in
your
feet and legs
(peripheral
artery
disease).
have
loss
of
sensation
with
agents that cause
heart failure.
have a
condition called
pheochromocytoma
(a
tumour
of
the adrenal
gland).
have
a
condition called
metabolic
acidosis
(abnormal
levels
o

Характеристики продукта

PRODUCT
MpNOGRAPH
Glnpo-erENoL
Atenolol
Tablets
Apotex
Standard
50
and
100
mg
Beta-adrenergic
receptor
blocking
agent
APOTEX
INC.
150
Signet
Drive
Weston,
Ontario
MgL
IT9
DATE
OF PREPARATION:
June
29,
1988
DATE
OF
REVISION:
November
t4,2016
0
EF
rru
ÅPPR0\Itn
IXPERT/O
ÀP
P
t
I
I
A
tl
û
U
TIIIT
A
Control
Number:TBD
1Q
o$t*
PRODUCT
MONOGRAPH
f,lnpo-nrENol
Atenolol
Tablets
APotex
Standard
50
and
100 mg
THERAPEUTIC
CLASSIFICATION
Beta-adrenergic
receptor
blocking
agent
ACTIONS
AND
CLINICAL
PHARMACOLOGY
Atenolol
is
a betar-selectlve,
beta
adrenergic
blocking
agent,
devoid
of
membrane
stabilizing
or
intrinsic
sympathomimetic
(partial
agonist)
activities.
lt
is
a racemic
mixture
and
the
betar-
óràpert¡eé
r"siOe
in the
Sþj
enantiomer.
Betar-selectivity
decreases
with
increasing
dose.
The
mechanism
of
the
antihypertensive
effect
has not
been
established.
Among the
factors
that
may
be
involved
are:
ã¡
competitive
ability
to
antagonize
catecholamine-induced
tachycardia
at
the
beta-receptor
sites
in
the
heart,
thus
decreasing
cardiac
ouiput
b)
inhibition
of
renin
release
by
the
kidneys
c)
inhibition
of
the
vasomotor
centres
The
mechanism
of
the
anti-anginal
effect
is
also
uncertain.
An
important
factor
may
be
the
reduction
of
myocardial
oxygeñ
requirements
by
blocking
catecholamine-induced
increases
in
heart
rate,
sysiolic
blood
prãssure, and
the
velocity
and
extent
of
myocardial
contraction.
ln
man
atenolol
reduces
both
isoproterenol-
and
exercise-induced
increases
in
heart
rate
over
the
Uor"
r.ng"
of
50
to
200
mg.
At
an
oraldose
of
100
mg
the
betar
blocking
effects
persist
for
at
least
24
ñorrs; the
reductiõn
in
exercise-induced
heart
rate
increase
being
about
37o/o
ând
13o/o,
Z
and
24
hours
after
dosing,
respectively.
The
logarithm
of
the
plasma
atenolol
level
correlates
with
the
degree
of
betar
blõckade
but
not
with
the
antihypertensive
effect.
Pharmacokinetics
Approximately
40
to
50o/o
of
an
oral
dose
of atenolol
is absorbed
from
the
gastroíntestinaltract,
tire
remainder
o"ing
excreted
unchanged
in
the