Tazocin EF

Țară: Australia

Limbă: engleză

Sursă: Department of Health (Therapeutic Goods Administration)

Ingredient activ:

Tazobactam; Piperacillin; Tazobactam sodium; Piperacillin sodium

Disponibil de la:

Pfizer Australia Pty Ltd

Clasă:

Medicine Registered

Prospect

TAZOCIN EF
®

_Piperacillin/tazobactam for Injection_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about TAZOCIN EF. It
does not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you taking TAZOCIN EF
against the benefits this medicine is
expected to have for you.
IF YOU HAVE ANY QUESTIONS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET.
You may need to read it again.
WHAT TAZOCIN EF IS
USED FOR
The name of your medicine is
TAZOCIN EF. It contains the active
ingredients piperacillin and
tazobactam. They belong to a group
of antibiotics called penicillins that
work by killing bacteria.
Piperacillin is an antibiotic that kills
many types of bacteria. Tazobactam
belongs in the penicillin group but
does not have activity against
bacteria. It helps piperacillin to
overcome bacteria which have
become resistant to piperacillin.
TAZOCIN EF is active against
bacteria which cause serious
infections such as: -
•
Chest infections
•
Urine infections
•
Stomach infections
•
Skin infections
•
Gynaecological infections
•
Septicaemia (blood poisoning).
It is also used to treat many other
infections.
In hospitalised children aged 2 to 12
years, TAZOCIN EF is used to treat
serious infections in the abdomen.
TAZOCIN EF is not recommended
to treat abdominal infections in
children under 2 years.
TAZOCIN EF will not work against
infections caused by viruses such as
colds or flu.
This medicine is available only with
a doctor's prescription.
TAZOCIN EF is not addictive.
BEFORE YOU ARE GIVEN
TAZOCIN EF
_WHEN YOU MUST NOT RECEIVE_
_TAZOCIN EF_
DO NOT HAVE TAZOCIN EF IF:
1. YOU HAVE EVER HAD AN ALLERGIC
REACTION TO:
•
piperacillin, tazobactam, or any
other penicillin antibiotics
•
any antibiotic in the
cephalosporin group
•
medicines called beta-lactamase
inhibitors.
Some of the symptoms of an all

Caracteristicilor produsului

Version: pfptazev10712 
Supersedes:  pfptazev10411 

Page 1 of 18 
TAZOCIN EF


PRODUCT INFORMATION 
NAME OF THE MEDICINE 
TAZOCIN EF; piperacillin / tazobactam injection 2.0g/0.25g*; and 
TAZOCIN EF; piperacillin / tazobactam injection 4.0g/0.5g. 
Piperacillin  sodium  is  derived  from  D(-)-

-aminobenzylpenicillin.  The  chemical  name  of 
piperacillin 
sodium 
is 
sodium 
(2S,5R,6R)-6-[(R)-2-(4-ethyl-2,3-dioxo-1-piperazine-
carboxamido)-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-
carboxylic acid.  The empirical  formula is  C
23
H
26
N
5
NaO
7
S and the molecular weight is 539.54. 
Its structural formula is: 
N
O
O
N
O
N
H
O
H
N
O
N
S
CH
3
H
H
H
3
C
CH
3
CO
2
Na

Piperacillin sodium 
CAS Registry Number: 59703-84-3 
Tazobactam  sodium  is  a  derivative  of  the  penicillin  nucleus.    Chemically,  tazobactam  is  a 
penicillanic  acid  sulfone.    Its  chemical  name  is  sodium  (2S-(2

,3

,5

)-3-methyl-7-oxo-3-(1H-
1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]  heptane-2-carboxylic  acid  4,4-dioxide.  The 
empirical formula is C
10
H
11
N
4
NaO
5
S and the molecular weight is 322.28. The chemical structure 
of tazobactam sodium is: 
N
H
COON
a
N
N
N
CH
3
S
O
O
O

Tazobactam sodium 
CAS Registry Number: 89785-84-2 
Version: pfptazev10712 
Supersedes:  pfptazev10411 

Page 2 of 18 
DESCRIPTION 
TAZOCIN  EF  is  an  injectable  antibacterial  combination,  consisting  of  the  semisynthetic 
antibiotic piperacillin sodium and the 

-lactamase inhibitor tazobactam sodium, for intravenous 
administration. 
TAZOCIN EF is available as a white to off-white sterile, cryodesiccated powder of piperacillin 
and tazobactam as the sodium salts packaged in glass vials.  Each vial of TAZOCIN EF contains 
a total  of 2.79 mEq  (64 mg) of sodium p