देश: ऑस्ट्रेलिया
भाषा: अंग्रेज़ी
स्रोत: Department of Health (Therapeutic Goods Administration)
Tazobactam; Piperacillin; Tazobactam sodium; Piperacillin sodium
Pfizer Australia Pty Ltd
Medicine Registered
TAZOCIN EF ® _Piperacillin/tazobactam for Injection_ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about TAZOCIN EF. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking TAZOCIN EF against the benefits this medicine is expected to have for you. IF YOU HAVE ANY QUESTIONS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET. You may need to read it again. WHAT TAZOCIN EF IS USED FOR The name of your medicine is TAZOCIN EF. It contains the active ingredients piperacillin and tazobactam. They belong to a group of antibiotics called penicillins that work by killing bacteria. Piperacillin is an antibiotic that kills many types of bacteria. Tazobactam belongs in the penicillin group but does not have activity against bacteria. It helps piperacillin to overcome bacteria which have become resistant to piperacillin. TAZOCIN EF is active against bacteria which cause serious infections such as: - • Chest infections • Urine infections • Stomach infections • Skin infections • Gynaecological infections • Septicaemia (blood poisoning). It is also used to treat many other infections. In hospitalised children aged 2 to 12 years, TAZOCIN EF is used to treat serious infections in the abdomen. TAZOCIN EF is not recommended to treat abdominal infections in children under 2 years. TAZOCIN EF will not work against infections caused by viruses such as colds or flu. This medicine is available only with a doctor's prescription. TAZOCIN EF is not addictive. BEFORE YOU ARE GIVEN TAZOCIN EF _WHEN YOU MUST NOT RECEIVE_ _TAZOCIN EF_ DO NOT HAVE TAZOCIN EF IF: 1. YOU HAVE EVER HAD AN ALLERGIC REACTION TO: • piperacillin, tazobactam, or any other penicillin antibiotics • any antibiotic in the cephalosporin group • medicines called beta-lactamase inhibitors. Some of the symptoms of an all पूरा दस्तावेज़ पढ़ें
Version: pfptazev10712 Supersedes: pfptazev10411 Page 1 of 18 TAZOCIN EF PRODUCT INFORMATION NAME OF THE MEDICINE TAZOCIN EF; piperacillin / tazobactam injection 2.0g/0.25g*; and TAZOCIN EF; piperacillin / tazobactam injection 4.0g/0.5g. Piperacillin sodium is derived from D(-)- -aminobenzylpenicillin. The chemical name of piperacillin sodium is sodium (2S,5R,6R)-6-[(R)-2-(4-ethyl-2,3-dioxo-1-piperazine- carboxamido)-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- carboxylic acid. The empirical formula is C 23 H 26 N 5 NaO 7 S and the molecular weight is 539.54. Its structural formula is: N O O N O N H O H N O N S CH 3 H H H 3 C CH 3 CO 2 Na Piperacillin sodium CAS Registry Number: 59703-84-3 Tazobactam sodium is a derivative of the penicillin nucleus. Chemically, tazobactam is a penicillanic acid sulfone. Its chemical name is sodium (2S-(2 ,3 ,5 )-3-methyl-7-oxo-3-(1H- 1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0] heptane-2-carboxylic acid 4,4-dioxide. The empirical formula is C 10 H 11 N 4 NaO 5 S and the molecular weight is 322.28. The chemical structure of tazobactam sodium is: N H COON a N N N CH 3 S O O O Tazobactam sodium CAS Registry Number: 89785-84-2 Version: pfptazev10712 Supersedes: pfptazev10411 Page 2 of 18 DESCRIPTION TAZOCIN EF is an injectable antibacterial combination, consisting of the semisynthetic antibiotic piperacillin sodium and the -lactamase inhibitor tazobactam sodium, for intravenous administration. TAZOCIN EF is available as a white to off-white sterile, cryodesiccated powder of piperacillin and tazobactam as the sodium salts packaged in glass vials. Each vial of TAZOCIN EF contains a total of 2.79 mEq (64 mg) of sodium p पूरा दस्तावेज़ पढ़ें