PARANOR 500mg Tablet

País: Malásia

Língua: inglês

Origem: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Ingredientes ativos:

Paracetamol

Disponível em:

Noripharma Sdn. Bhd.

DCI (Denominação Comum Internacional):

Paracetamol

Unidades em pacote:

30 Tablets; 50 Tablets; 100 Tablets; 150 Tablets; 200 Tablets; 250 Tablets; 300 Tablets; 350 Tablets; 400 Tablets; 450 Tablets; 500 Tablets; 1000 Tablets; 10 Tablets; 20 Tablets

Fabricado por:

Noripharma Sdn. Bhd.

Folheto informativo - Bula

_Consumer Medication Information Leaflet (RiMUP)_
_ _
PARANOR 500MG TABLET
Paracetamol 500mg
1 | P a g e
WHAT IS IN THIS LEAFLET
1.
What PARANOR 500mg used
for
2.
How PARANOR 500mg works
3.
Before
you
use
PARANOR
500mg
4.
How to use PARANOR 500mg
5.
While you are using it
6.
Side effects
7.
Storage
and
Disposal
of
PARANOR 500mg
8.
Product Description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of Revision.
WHAT PARANOR 500MG USED FOR
PARANOR 500mg Tablet is used for
the relief of fever.
For the relief from mild to moderate
including:
headache,
migraine,
backache,
musculoskeletal
pain,
myalgia
and
neuralgia,
dysmenorrhea, pain of osteoarthritis,
toothache,
pain
after
dental
procedures/tooth
extraction,
pain
after vaccination and the discomfort
from
colds,
influenza
and
sore
throats.
HOW PARANOR 500MG WORKS
PARANOR
500mg
Tablet
has
analgesic (pain relief) and antipyretic
(anti-fever) properties.
BEFORE YOU USE PARANOR 500MG
-_WHEN YOU MUST NOT USE IT_
Do
not
take
PARANOR
500mg
Tablet
if
you
are
allergic
to
Paracetamol or Acetaminophen and
other ingredients. If you are not sure
whether you should start taking this
medicine,
talk
to
your
doctor
or
pharmacist.
_- BEFORE YOU START TO USE IT _
This product contains Paracetamol.
Do
not
take
other
Paracetamol
containing medicine at the same time.
Your doctor needs to know before
you take PARANOR 500mg Tablet

if you have kidney or liver problem.
PARANOR 500mg Tablet should
also be taken with care when you
take other medicines that affect the
liver.
Discuss
with
your
doctor
or
pharmacist first if you are pregnant or
breastfeeding.
Problems
in
human
have not been reported when taking
PARANOR
500mg
Tablet
during
pregnancy or breastfeeding.
_-TAKING OTHER MEDICINES _
Tell your doctor or pharmacist before
taking PARANOR 500mg Tablet, if
you are taking any other medicines,
including any that you buy without a
prescription
from
your
pharmacy,
supermarket or health food shop.
The effects of some medicines may
be affected if other
medicines are
used at the same tim

Características técnicas

Package Insert
1
PRODUCT NAME
PARANOR 500mg Tablet
COMPOSITION
Paracetamol
500mg/tablet
PRODUCT DESCRIPTION
A white to off white round film coated tablet with score line one side
and plain on the other side.
PHARMACODYNAMICS
Paracetamol is a centrally acting analgesic and antipyretic with
minimal anti-inflammatory properties
_ANALGESIC_-The mechanism of analgesic action has not been fully
determined. Paracetamol may act
predominantly by inhibiting prostaglandin synthesis in the central
nervous system (CNS) and, to a lesser
extent, through a peripheral action by blocking pain-impulse
generation._ _
The peripheral action may also be due to inhibition of prostaglandin
synthesis or to inhibition of the
synthesis or actions of other substances that sensitize pain receptors
to mechanical or chemical
stimulation
_ANTIPYRETIC_- Paracetamol act centrally on the hypothalamic
heat-regulating center to produce peripheral
vasodilatation resulting in increase blood flow through the skin,
sweating and heat loss._ _
Paracetamol reduces fever by inhibiting the formulation and release of
prostaglandins in the CNS and by
inhibiting endogenous pyrogens at the hypothalamic thermoregulatory
center.
PHARMACOKINETICS
Following oral administration paracetamol is rapidly absorbed.
Paracetamol absorption takes place
mainly in the small intestine and therefore the rate of absorption is
depending on the rate of gastric
emptying. It has been shown that drugs which delay gastric emptying
also delay the absorption of
paracetamol whereas metoclopramide (a drug which increases the rate of
gastric emptying) accelerates
absorption of the analgesic through the total amount absorbed doses
not increase.
The presence of food in the stomach has also been reported to reduce
the rate of absorption of
paracetamol. Alterations in gastric pH have no appreciable effect on
paracetamol absorption. During
absorption, the amount of paracetamol which is inactivated is
negligible and it has been shown that
paracetamol dose not affect gastric mucosal permeability an