IVERMECTIN solution

País: Estados Unidos

Língua: inglês

Origem: NLM (National Library of Medicine)

Ingredientes ativos:

Ivermectin (UNII: 8883YP2R6D) (Ivermectin - UNII:8883YP2R6D)

Disponível em:

Durvet, Inc.

DCI (Denominação Comum Internacional):

Ivermectin

Composição:

Ivermectin 5 mg in 5 L

Via de administração:

TOPICAL

Tipo de prescrição:

OTC

Indicações terapêuticas:

INDICATIONS IVERMECTIN (ivermectin topical solution) Pour-On applied at the recommended dose level of 500 mcg/kg is indicated for the effective treatment and control of these parasites. Gastrointestinal Roundworms Ostertagia ostertagi                (adults and L4 ) (including inhibited state) Haemonchus placei                (adults and L4 ) Trichostrongylus axei              (adults and L4 ) T. colubriformis                      (adults and L4 ) Cooperia oncophora                (adults and L4 ) Cooperia punctata                  (adults and L4 ) Cooperia surnabada                (adults and L4 ) Strongyloides papillosus         (adults) Oesophagostomum radiatum   (adults and L4 ) Trichuris spp.                         (adults) Lungworms Dictyocaulus viviparus             (adults and L4 ) Cattle Grubs                         (parasitic stages) Hypoderma bovis H. lineatum Mites Sarcoptes scabiei var. bovis Lice Linognathus vituli Haematopinus eurysternus Damalinia bovis Solenopotes capillatus Horn Flies Haem

Resumo do produto:

HOW SUPPLIED IVERMECTIN (ivermectin topical solution) Pour-On is available in a 33.8 fl oz/1 Liter Bottle with a measure-squeeze-pour system, an 84.5 fl oz/2.5 Liter Pack, and a 169 fl oz/5 Liter Pack intended for use with appropriate automatic dosing equipment.

Status de autorização:

Abbreviated New Animal Drug Application

Características técnicas

IVERMECTIN- IVERMECTIN SOLUTION
DURVET, INC.
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IVERMECTIN
(IVERMECTIN TOPICAL SOLUTION)
POUR-ON For Cattle
APPROVED BY FDA UNDER ANADA 200-318
CONTAINS 5 MG IVERMECTIN/ML
PARAS ITICIDE
CONSULT YOUR VETERINARIAN FOR ASSISTANCE IN THE DIAGNOSIS, TREATMENT
AND CONTROL OF PARASITISM.
INTRODUCTION
IVERMECTIN (ivermectin topical solution) Pour-On delivers internal and
external parasite control in
one convenient low-volume application. IVERMECTIN Pour-On contains
ivermectin, a unique chemical
entity.
MODE OF ACTION
Ivermectin is a member of the macrocyclic lactone class of
endectocides which have a unique mode of
action. Compounds of the class binds selectively and with high
affinity to glutamate-gated chloride ion
channels which occur in invertebrate nerve and muscle cells. This
leads to an increase in the
permeability of the cell membrane to chloride ions with
hyperpolarization of the nerve or muscle cell,
resulting in paralysis and death of the parasite. Compounds of this
class may also interact with other
ligand-gated chloride channels, such as those gated by the
neurotransmitter gamma-aminobutyric acid
(GABA). The margin of safety for compounds of this class is
attributable to the fact that mammals do
not have the glutamate-gated chloride channel, the macrocyclic
lactones have a low affinity for other
mammalian ligand-gated chloride channel and they do not readily cross
the blood-brain barrier.
INDICATIONS
IVERMECTIN (ivermectin topical solution) Pour-On applied at the
recommended dose level of 500
mcg/kg is indicated for the effective treatment and control of these
parasites.
GASTROINTESTINAL ROUNDWORMS
_Ostertagia ostertagi_ (adults and L )
(including inhibited state)
_Haemonchus placei _ (adults and L )
_Trichostrongylus axei _ (adults and L )
_T. colubriformis _ (adults and L )
_Cooperia oncophora_ (adults and L )
_Cooperia punctata _ (adults and L )
_Cooperia surnabada_ (adults and L )
_Strongyloides papillosus_ (adults)
_Oesophagostomum radiatum_ (adults and L )
_Trichuris spp. _ (adults)
LUNGWORMS
4