Country: Bandaríkin
Tungumál: enska
Heimild: NLM (National Library of Medicine)
Ivermectin (UNII: 8883YP2R6D) (Ivermectin - UNII:8883YP2R6D)
Durvet, Inc.
Ivermectin
Ivermectin 5 mg in 5 L
TOPICAL
OTC
INDICATIONS IVERMECTIN (ivermectin topical solution) Pour-On applied at the recommended dose level of 500 mcg/kg is indicated for the effective treatment and control of these parasites. Gastrointestinal Roundworms Ostertagia ostertagi (adults and L4 ) (including inhibited state) Haemonchus placei (adults and L4 ) Trichostrongylus axei (adults and L4 ) T. colubriformis (adults and L4 ) Cooperia oncophora (adults and L4 ) Cooperia punctata (adults and L4 ) Cooperia surnabada (adults and L4 ) Strongyloides papillosus (adults) Oesophagostomum radiatum (adults and L4 ) Trichuris spp. (adults) Lungworms Dictyocaulus viviparus (adults and L4 ) Cattle Grubs (parasitic stages) Hypoderma bovis H. lineatum Mites Sarcoptes scabiei var. bovis Lice Linognathus vituli Haematopinus eurysternus Damalinia bovis Solenopotes capillatus Horn Flies Haem
HOW SUPPLIED IVERMECTIN (ivermectin topical solution) Pour-On is available in a 33.8 fl oz/1 Liter Bottle with a measure-squeeze-pour system, an 84.5 fl oz/2.5 Liter Pack, and a 169 fl oz/5 Liter Pack intended for use with appropriate automatic dosing equipment.
Abbreviated New Animal Drug Application
IVERMECTIN- IVERMECTIN SOLUTION DURVET, INC. ---------- IVERMECTIN (IVERMECTIN TOPICAL SOLUTION) POUR-ON For Cattle APPROVED BY FDA UNDER ANADA 200-318 CONTAINS 5 MG IVERMECTIN/ML PARAS ITICIDE CONSULT YOUR VETERINARIAN FOR ASSISTANCE IN THE DIAGNOSIS, TREATMENT AND CONTROL OF PARASITISM. INTRODUCTION IVERMECTIN (ivermectin topical solution) Pour-On delivers internal and external parasite control in one convenient low-volume application. IVERMECTIN Pour-On contains ivermectin, a unique chemical entity. MODE OF ACTION Ivermectin is a member of the macrocyclic lactone class of endectocides which have a unique mode of action. Compounds of the class binds selectively and with high affinity to glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells. This leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite. Compounds of this class may also interact with other ligand-gated chloride channels, such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA). The margin of safety for compounds of this class is attributable to the fact that mammals do not have the glutamate-gated chloride channel, the macrocyclic lactones have a low affinity for other mammalian ligand-gated chloride channel and they do not readily cross the blood-brain barrier. INDICATIONS IVERMECTIN (ivermectin topical solution) Pour-On applied at the recommended dose level of 500 mcg/kg is indicated for the effective treatment and control of these parasites. GASTROINTESTINAL ROUNDWORMS _Ostertagia ostertagi_ (adults and L ) (including inhibited state) _Haemonchus placei _ (adults and L ) _Trichostrongylus axei _ (adults and L ) _T. colubriformis _ (adults and L ) _Cooperia oncophora_ (adults and L ) _Cooperia punctata _ (adults and L ) _Cooperia surnabada_ (adults and L ) _Strongyloides papillosus_ (adults) _Oesophagostomum radiatum_ (adults and L ) _Trichuris spp. _ (adults) LUNGWORMS 4 Lestu allt skjalið