CHEWABLE DAILY LOW DOSE ASA TABLET (CHEWABLE)

País: Canadá

Língua: inglês

Origem: Health Canada

Ingredientes ativos:

ACETYLSALICYLIC ACID

Disponível em:

PHARMASCIENCE INC

Código ATC:

B01AC06

DCI (Denominação Comum Internacional):

ACETYLSALICYLIC ACID

Dosagem:

81MG

Forma farmacêutica:

TABLET (CHEWABLE)

Composição:

ACETYLSALICYLIC ACID 81MG

Via de administração:

ORAL

Unidades em pacote:

30/120/150/180

Tipo de prescrição:

OTC

Área terapêutica:

SALICYLATES

Resumo do produto:

Active ingredient group (AIG) number: 0101169013; AHFS:

Status de autorização:

CANCELLED POST MARKET

Data de autorização:

2020-01-10

Características técnicas

PRODUCT MONOGRAPH
CHEWABLE DAILY LOW DOSE ASA
(Acetylsalicylic acid chewable tablets, USP)
81 mg
Analgesic, anti-inflammatory, antipyretic and
platelet aggregation inhibitor
PHARMASCIENCE INC.
Date of Preparation:
6111 Royalmount Ave, Suite
#
100
April 5, 2012
Montreal, Quebec
H4P2T4
Submission Control No: 154310
PRODUCT MONOGRAPH
CHEWABLE DAILY LOW DOSE ASA
(Acetylsalicylic acid chewable tablets, USP)
81 mg
THERAPEUTIC OR PHARMACOLOGICAL CLASSIFICATION
Analgesic, anti-inflammatory, anti-pyretic and platelet aggregation
inhibitor.
ACTION AND CLINICAL PHARMACOLOGY
ASA interferes with the production of prostaglandins in various organs
and tissues through
acetylation of the enzyme cyclo-oxygenase. Prostaglandins are
themselves powerful irritants and
produce headaches and pain on injection in man. Prostaglandins also
appear to sensitize pain
receptors to other noxious substances such as histamine and
bradykinin. By preventing the
synthesis and release of prostaglandins in inflammation, ASA may avert
the sensitization of pain
receptors.
The antipyretic activity of ASA is due to its ability to interfere
with the
production of
prostaglandin E
1
in the brain. Prostaglandin E
1
is one of the most powerful pyretic agents
known.
The inhibition of platelet aggregation by ASA is due to its ability to
interfere with the production
of
thromboxane A
2
within
the
platelet.
Thromboxane A
2
is
largely
responsible
for
the
aggregating properties of platelets.
3
INDICATIONS AND CLINICAL USE
Acetylsalicylic acid (ASA) is indicated for the relief of pain, fever
and inflammation of a variety
of conditions such as influenza, common cold, low back and neck pain,
dysmenorrhea, headache,
toothache, sprains and strains, fractures, myositis, neuralgia,
synovitis, arthritis, bursitis, burns,
injuries, following surgical and dental procedures.
CHEWABLE DAILY LOW DOSE ASA 81 mg are also indicated for the following
uses, based
on its platelet aggregation inhibitory properties:
-For reducing the risk of morbidity and death in patients with
unstable