Kraj: Malezja
Język: angielski
Źródło: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
TYLOSIN TARTRATE
Y.S.P. INDUSTRIES (M) SDN. BHD.
TYLOSIN TARTRATE
10.00 mcg/mL; 150.00 mcg/mL; 750.00 mcg/mL
Y.S.P. INDUSTRIES VIETNAM CO., LTD
TYLOSIN WATER SOLUBLE POWDER 667mg/g INGREDIENT(S): Each g contains : Tylosin (as Tylosin tartrate)……….….……………....................... 667mg PHARMACOLOGY (SUMMARY OF PHARMACODYNAMICS AND PHARMACOKINETICS): Tylosin is thought to have the same mechanism of action as erythromycin (binds to 50S ribosome and inhibits protein synthesis). It is a bacteriostatic antibiotic. Tylosin tartrate is well absorbed from the GI tract, primarily from the intestine. Tylosin is well distributed in the body after systemic absorption, with the exception of penetration into the CSF. The volume of distribution of tylosin is reportedly 1.7L/kg in small animals and 1~2.3L/kg in cattle. In lactating dairy cattle, the milk to plasma ratio is reported to be between 1 and 5.4. Tylosin is eliminated in the urine and bile apparently as unchanged drug. The elimination half-life of tylosin is reportedly 54 minutes in small animals, 139 minutes in newborn calves, and 64 minutes in calves 2 months of age or older. INDICATION(S): For the prevention and treatment of bovine pneumonia associated with bovine respiratory Mycoplasma or _Pasteurella multocida _sensitive to tylosin. For the control of _Mycoplasma _ _synoviae_ airsacculitis in chickens and _Mycoplasma gallisepticum _S6 in chickens and turkeys. For the prevention and control of enzootic pneumonia, swine dysentery and other scours caused by organisms (e.g. _Lawsonia intracellularis)_ sensitive to tylosin, in pigs. As an aid in the control of outbreaks of necrotic enteritis caused by _Clostridium perfringens_ in chickens. TARGET SPECIES Chickens, turkeys, bovine, calves and swine. DOSAGE AND ADMINISTRATION: Chickens and turkeys: For chronic respiratory disease (ie Mycoplasma synoviae and Mycoplasma gallisepticum): The dose ranging from 50-200mg/kg body weight. For aid in controlling outbreaks of necrotic enteritis caused by _ Clostridium perfringes_: 20-50mg tylosin/kg bodyweight. Treatment may be administered for 1~5 days depending upon severity of infection. Swine: For swine Przeczytaj cały dokument