Tylosin Water Soluble Powder 667mgg

Riik: Malaisia

keel: inglise

Allikas: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Toimeaine:

TYLOSIN TARTRATE

Saadav alates:

Y.S.P. INDUSTRIES (M) SDN. BHD.

INN (Rahvusvaheline Nimetus):

TYLOSIN TARTRATE

Ühikuid pakis:

10.00 mcg/mL; 150.00 mcg/mL; 750.00 mcg/mL

Valmistatud:

Y.S.P. INDUSTRIES VIETNAM CO., LTD

Toote omadused

TYLOSIN
WATER SOLUBLE POWDER 667mg/g
INGREDIENT(S):
Each g contains :
Tylosin (as Tylosin
tartrate)……….….……………....................... 667mg
PHARMACOLOGY
(SUMMARY
OF
PHARMACODYNAMICS
AND
PHARMACOKINETICS):
Tylosin is thought to have the same mechanism of action as
erythromycin
(binds to 50S ribosome and inhibits protein synthesis). It is a
bacteriostatic
antibiotic.
Tylosin tartrate is well absorbed from the GI tract, primarily from
the intestine.
Tylosin is well distributed in the body after systemic absorption,
with the
exception of penetration into the CSF. The volume of distribution of
tylosin is
reportedly 1.7L/kg in small animals and 1~2.3L/kg in cattle. In
lactating dairy
cattle, the milk to plasma ratio is reported to be between 1 and 5.4.
Tylosin is
eliminated
in
the
urine
and
bile
apparently
as
unchanged
drug.
The
elimination half-life of tylosin is reportedly 54 minutes in small
animals, 139
minutes in newborn calves, and 64 minutes in calves 2 months of age or
older.
INDICATION(S):
For the prevention and treatment of bovine pneumonia associated with
bovine respiratory Mycoplasma or _Pasteurella multocida _sensitive to
tylosin.
For
the
control
of
_Mycoplasma _
_synoviae_
airsacculitis
in
chickens
and
_Mycoplasma gallisepticum _S6 in chickens and turkeys.
For the prevention and control of enzootic pneumonia, swine dysentery
and
other scours caused by organisms (e.g. _Lawsonia intracellularis)_
sensitive to
tylosin, in pigs.
As
an
aid
in
the
control
of
outbreaks
of
necrotic
enteritis
caused
by
_Clostridium perfringens_ in chickens.
TARGET SPECIES
Chickens, turkeys, bovine, calves and swine.
DOSAGE AND ADMINISTRATION:
Chickens and turkeys:
For chronic respiratory disease (ie Mycoplasma synoviae and Mycoplasma
gallisepticum): The dose ranging from 50-200mg/kg body weight. For aid
in
controlling outbreaks of necrotic enteritis caused by _ Clostridium
perfringes_:
20-50mg tylosin/kg bodyweight. Treatment may be administered for 1~5
days depending upon severity of infection.
Swine:
For swine