Kraj: Kanada
Język: angielski
Źródło: Health Canada
HYALURONATE SODIUM
DECHRA LTD
17MG
SOLUTION
HYALURONATE SODIUM 17MG
INTRA-ARTICULAR
3ML
Prescription
HORSES
Active ingredient group (AIG) number: 0115449003
APPROVED
2010-10-05
Dechra September 28, 2023 HY-50 tray lid Sterile / Stérile DIN 02238566 Veterinary Use Only / Usage vétérinaire seulement PR HY-50® 17 mg/mL Hyaluronate sodium injection / Hyaluronate de sodium solution injectable For intra-articular or intravenous use in horses. / Pour injection intra-articulaire ou intraveineuse chez le cheval. Horse picto 3 mL Dechra Ltd. Imported and distributed by / Importé et distribué par: Dechra Veterinary Products Inc. Lot : EXP : Dechra September 28, 2023 _HY-50_Package Insert_English _ DIN 02238566 PR HY-50® 17 mg/mL (51 mg/3 mL) Hyaluronate sodium injection Veterinary Use Only Sterile DESCRIPTION HY-50 is a highly purified, sterile, pyrogen-free aqueous solution of hyaluronate sodium derived by a fermentation process using _Streptococcus _spp. and then purified to yield a product which is essentially free of protein and nucleic acids. The molecular formula is [C 14 H 20 O 11 N 1 - Na + ] n . Each mL contains: hyaluronate sodium 17 mg; sodium chloride 7.57 mg; sodium phosphate dibasic 3.78 mg; sodium phosphate monobasic 0.45 mg; and water for injection q.s. CHEMISTRY: Hyaluronate sodium is the sodium salt of hyaluronic acid, a highly polymerized, non-sulphated acid mucopolysaccharide or glycosaminoglycan composed of equimolar amounts of D-glucuronic acid and N- acetylglucosamine linked together by glycosidic bonds. Hyaluronate possesses a negative charge which enables it to bind readily to other substances such as water, ions, proteins and solutes. The hyaluronate produced by bacteria is structurally and chemically indistinguishable from mammalian hyaluronate. PHARMACOLOGY Hyaluronate is a naturally occurring substance present in connective tissue, skin, vitreous humour, synovial fluid and umbilical cord in all mammals. Hyaluronate is synthesized by synoviocytes and is responsible for the viscoelastic characteristic of synovial fluid. Synovial fluid hyaluronate functions as a lubricant of the intra-articular soft tissues, aids in providing nourishment and removing waste products Przeczytaj cały dokument