HY-50 SOLUTION

Nazione: Canada

Lingua: inglese

Fonte: Health Canada

Principio attivo:

HYALURONATE SODIUM

Commercializzato da:

DECHRA LTD

Dosaggio:

17MG

Forma farmaceutica:

SOLUTION

Composizione:

HYALURONATE SODIUM 17MG

Via di somministrazione:

INTRA-ARTICULAR

Confezione:

3ML

Tipo di ricetta:

Prescription

Gruppo terapeutico:

HORSES

Dettagli prodotto:

Active ingredient group (AIG) number: 0115449003

Stato dell'autorizzazione:

APPROVED

Data dell'autorizzazione:

2010-10-05

Foglio illustrativo

Dechra September 28, 2023
HY-50 tray lid
Sterile / Stérile
DIN 02238566
Veterinary Use Only / Usage vétérinaire seulement
PR
HY-50® 17 mg/mL
Hyaluronate sodium injection /
Hyaluronate de sodium solution injectable
For intra-articular or intravenous use in horses. /
Pour injection intra-articulaire ou intraveineuse chez le cheval.
Horse picto
3 mL
Dechra Ltd.
Imported and distributed by / Importé et distribué par: Dechra
Veterinary Products Inc.
Lot :
EXP :
Dechra September 28, 2023
_HY-50_Package Insert_English _
DIN 02238566
PR
HY-50® 17 mg/mL (51 mg/3 mL)
Hyaluronate sodium injection
Veterinary Use Only
Sterile
DESCRIPTION
HY-50 is a highly purified, sterile, pyrogen-free aqueous solution of
hyaluronate sodium derived by a fermentation
process using _Streptococcus _spp. and then purified to yield a
product which is essentially free of protein and
nucleic acids.
The molecular formula is [C
14
H
20
O
11
N
1
-
Na
+
]
n
.
Each mL contains: hyaluronate sodium 17 mg; sodium chloride 7.57 mg;
sodium phosphate dibasic 3.78 mg;
sodium phosphate monobasic 0.45 mg; and water for injection q.s.
CHEMISTRY:
Hyaluronate sodium is the sodium salt of hyaluronic acid, a highly
polymerized, non-sulphated acid
mucopolysaccharide or glycosaminoglycan composed of equimolar amounts
of D-glucuronic acid and N-
acetylglucosamine linked together by glycosidic bonds. Hyaluronate
possesses a negative charge which enables it
to bind readily to other substances such as water, ions, proteins and
solutes. The hyaluronate produced by
bacteria is structurally and chemically indistinguishable from
mammalian hyaluronate.
PHARMACOLOGY
Hyaluronate is a naturally occurring substance present in connective
tissue, skin, vitreous humour, synovial fluid
and umbilical cord in all mammals. Hyaluronate is synthesized by
synoviocytes and is responsible for the
viscoelastic characteristic of synovial fluid. Synovial fluid
hyaluronate functions as a lubricant of the intra-articular
soft tissues, aids in providing nourishment and removing waste
products