CARBACCORD

Kraj: Australia

Język: angielski

Źródło: Department of Health (Therapeutic Goods Administration)

Składnik aktywny:

Carboplatin

Dostępny od:

Accord Healthcare Pty Ltd

Klasa:

Medicine Registered

Ulotka dla pacjenta

CARBACCORD 10 MG/ML CARBOPLATIN SOLUTION FOR INJECTION 5 ML, 15 ML 
AND 45 ML VIAL  
CONSUMER MEDICINE INFORMATION 

 VERSION-1.0 

2011                                    

  Page 1 of 5 
CARBACCORD (CARBOPLATIN) INJECTION 10 MG/ML, 5 ML, 15 ML AND 45 ML  

Carboplatin _(carb-o-PLAT-in)_

CONSUMER MEDICINE INFORMATION  

WHAT IS IN THIS LEAFLET

This leaflet answers some 
common questions about 
Carbaccord (carboplatin) 
Injection. It does not contain all 
the available information. It 
does not take the place of 
talking to your doctor or 
pharmacist.  

All medicines have risks and 
benefits. Your doctor has 
weighed the risks of you being 
given carboplatin against the 
benefits they expect it will have 
for you. 

IF YOU HAVE ANY CONCERNS 
ABOUT BEING GIVEN THIS 
MEDICINE, ASK YOUR DOCTOR OR 
PHARMACIST.  
KEEP THIS LEAFLET. 
You may need to read it again. 

WHAT CARBACCORD 
(CARBOPLATIN) 
INJECTION IS USED FOR  

This medicine is used to treat: 
•  ovarian cancer  
•  cancer of the testes 
•  some types of lung cancer 
•  cancer of the brain and/or 
spinal cord 
•  cancer of the head and neck 
•  neuroblastoma (a cancer of 
the nerves and adrenal 
glands) 
•  a type of cancer called 
sarcoma.  

Carboplatin belongs to a group 
of medicines called 
antineoplastic or cytotoxic 
medicines. You may also hear 
of these being called 
chemotherapy medicines. This 
medicine is classified

Charakterystyka produktu

CARBACCORD 10 mg/mL carboplatin solution for injection  
5 mL, 15 mL and 45 mL vial                      

   Version-1.0      
2011                                    

                           Page 1 of 10 

PRODUCT INFORMATION 
CARBACCORD (CARBOPLATIN) SOLUTION FOR INJECTION 

NAME OF THE MEDICINE 
Carboplatin 

TRADE NAME CARBACCORD Solution for Injection 

DESCRIPTION 
Carboplatin is
(SP-4-2)-diammine[cyclobutan-1,1-dicarboxylato(2-)-0,0’]platin. It
is a 
colourless, crystalline powder, sparingly soluble in water,
very slightly soluble in acetone 
and in alcohol. 

The chemical structure of carboplatin is shown below:  

Molecular Formula: C
6
H
12
N
2
O
4
Pt 
Molecular Weight: 371.3 
CAS Number: 41575-94-4 

Carboplatin Solution for Injection is a sterile, hypotonic,
preservative-free solution of 
carboplatin in Water for Injections Ph. Eur. The pH of the injection
ranges between 5.0 
and 7.0. Carboplatin Solution for Injection is presented in vials
containing 50 mg/5 mL, 
150 mg/15 mL and 450 mg/45 mL.  

PHARMACOLOGY 
Carboplatin, an analogue of cisplatin, is an antineoplastic agent
which interferes with 
DNA intrastrand and interstrand crosslinks in cells exposed to the
medicine. DNA 
reactivity has been correlated with cytotoxicity.  

PHARMACOKINETICS  
After a one-hour infusion of the medicine (dose range 20 to 520
milligrams/m
2
) plasma 
levels of total platinum and ultrafilterable (free) platinum decay
biphasically following 
first order kinetics. For ultrafilterable platinum reported
values for the initial phase of the 
half life (t 
alpha 1/2
) are about 90 minutes and in the later phase t