Land: Malaysia
Språk: engelsk
Kilde: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
CETIRIZINE DIHYDROCHLORIDE
MALAYSIAN PHARMACEUTICAL INDUSTRIES SDN. BHD.
CETIRIZINE DIHYDROCHLORIDE
120 ml
MALAYSIAN PHARMACEUTICAL INDUSTRIES SDN. BHD.
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ 1 URTIRIZINE SYRUP 5MG/5ML Cetirizine dihydrochloride (5mg/5ml) WHAT IS IN THIS LEAFLET: 1. What Urtirizine Syrup is used for 2. How Urtirizine Syrup works 3. Before you use Urtirizine Syrup 4. How to use Urtirizine Syrup 5. While you are using it 6. Side effects 7. Storage and Disposal of Urtirizine Syrup 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of Revision WHAT URTIRIZINE SYRUP IS USED FOR Urtirizine Syrup is indicated for the symptomatic treatment of seasonal rhinitis (inflammation of the inside of the nose), persistent allergic rhinitis (allergic rhinitis for prolonged period) and urticaria (raised, itchy rash that appears on the skin) of allergic origin. HOW URTIRIZINE SYRUP WORKS Cetirizine dihydrochloride is the active ingredient of Urtirizine Syrup. It is a type of anti-histamine. Histamine is a chemical released into the body during an allergic reaction. It causes itching and inflammation. Urtirizine Syrup works by blocking the effects of the naturally occurring chemical histamine in your body. Urtirizine Syrup markedly reduces respiratory hyperactivity to histamine in the asthmatic person. It also reduces the allergic reaction induced by specific allergens. BEFORE YOU USE URTIRIZINE SYRUP - _When you must not use it: _ If you are allergic (hypersensitive) to cetirizine dihydrochloride or to an antihistamine or any of the other ingredients of Urtirizine Syrup. If you are breast feeding as it is found in breast milk. If you have porphyria (a rare hereditary disease in which the blood pigment hemoglobin is abnormally metabolized). If you are in the first three months of pregnancy This product contains aspartame. As such, its intake should be restricted by those people with phenylketouria. - _Before you start to take it: _ You must tell your doctor if: you have allergies to any medicine which you have taken previously to treat your current condition. you are pregnant, trying to become pregna Les hele dokumentet
7155-05 URTIRIZINE TABLETS 10MG URTIRIZINE SYRUP 5MG/5ML NAME AND STRENGTH OF ACTIVE SUBSTANCE: URTIRIZINE TABLETS 10MG Each tablet contains: Cetirizine diHCL…………………………………………………10mg URTIRIZINE SYRUP 5MG/5ML Each 5ml contains: Cetirizine diHCL…………………………………………………5mg PRODUCT DESCRIPTION: URTIRIZINE TABLETS 10MG A white, scored, oblong tablet of size 10 x 4mm. URTIRIZINE SYRUP 5MG/5ML A colorless, liquid with pineapple flavor and sweet taste. PHARMACODYNAMICS Cetirizine hydrochloride, a human metabolite of hydroxyzine, is a potent antihistamine that selectively inhibits the effect of peripheral H (1)-receptors. Cetirizine belongs to the piperazine class of antihistamines and is the major carboxylated metabolite of hydroxyzine. However, it is less lipophilic than hydroxyzine and thus less likely to distribute into the central nervous system (CNS) and produce sedation. Generally, antihistamines contain 1 or 2 heterocyclic or aromatic rings attached to the side chain of histamine. Cetirizine has more polar or less lipophilic functional groups attached to the ethylamine side chain which has resulted in less CNS penetration, greater selectivity for the H1-receptor, and less anticholinergic side effects. Cetirizine may also have a modulatory effect on inflammatory cells by inhibiting eosinophil migration or eosinophilotactic mediators. Additionally, cetirizine may also have inhibitory effects on other infiltrating inflammatory cells, such as neutrophils. Cetirizine has shown to be safe for allergic patients with mild to moderate asthma and does not cause prolongation of QT interval. PHARMACOKINETICS:_ _ _Absorption _ Cetirizine is rapidly absorbed from the gastrointestinal tract after oral doses and peak plasma concentrations occur within about an hour. Food delays the time to peak plasma concentrations but does not decrease the amount of drug absorbed. Bioavailability, oral : 70%. The extent of bioavailability is similar when cetirizine is given a Les hele dokumentet