URTIRIZINE SYRUP 5MG5ML

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

CETIRIZINE DIHYDROCHLORIDE

Boleh didapati daripada:

MALAYSIAN PHARMACEUTICAL INDUSTRIES SDN. BHD.

INN (Nama Antarabangsa):

CETIRIZINE DIHYDROCHLORIDE

Unit dalam pakej:

120 ml

Dikeluarkan oleh:

MALAYSIAN PHARMACEUTICAL INDUSTRIES SDN. BHD.

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
1
URTIRIZINE SYRUP 5MG/5ML
Cetirizine dihydrochloride (5mg/5ml)
WHAT IS IN THIS LEAFLET:
1.
What Urtirizine Syrup is used for
2.
How Urtirizine Syrup works
3.
Before you use Urtirizine Syrup
4.
How to use Urtirizine Syrup
5.
While you are using it
6.
Side effects
7.
Storage
and
Disposal
of
Urtirizine Syrup
8.
Product Description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of Revision
WHAT URTIRIZINE SYRUP IS USED FOR
Urtirizine Syrup is indicated for the
symptomatic
treatment
of
seasonal
rhinitis (inflammation of the inside of
the nose), persistent allergic rhinitis
(allergic rhinitis for prolonged period)
and urticaria (raised, itchy rash that
appears on the skin) of allergic origin.
HOW URTIRIZINE SYRUP WORKS
Cetirizine
dihydrochloride
is
the
active ingredient of Urtirizine Syrup.
It
is
a
type
of
anti-histamine.
Histamine is a chemical released into
the body during an allergic reaction.
It causes itching and inflammation.
Urtirizine Syrup works by blocking
the effects of the naturally occurring
chemical
histamine
in
your
body.
Urtirizine
Syrup
markedly
reduces
respiratory hyperactivity to histamine
in
the
asthmatic
person.
It
also
reduces the allergic reaction induced
by specific allergens.
BEFORE YOU USE URTIRIZINE SYRUP
-
_When you must not use it: _

If
you
are
allergic
(hypersensitive) to cetirizine
dihydrochloride
or
to
an
antihistamine or any of the
other
ingredients
of
Urtirizine Syrup.

If you are breast feeding as it
is found in breast milk.

If you have porphyria (a rare
hereditary disease in which
the
blood
pigment
hemoglobin
is
abnormally
metabolized).

If you are in the first three
months of pregnancy

This
product
contains
aspartame.
As
such,
its
intake
should
be
restricted
by
those
people
with
phenylketouria.
-
_Before you start to take it: _
You must tell your doctor if:

you
have
allergies
to
any
medicine
which
you
have
taken
previously
to
treat
your current condition.

you are pregnant, trying to
become pregna

Ciri produk

7155-05
URTIRIZINE TABLETS 10MG
URTIRIZINE SYRUP 5MG/5ML
NAME AND STRENGTH OF ACTIVE SUBSTANCE:
URTIRIZINE TABLETS 10MG
Each tablet contains:
Cetirizine
diHCL…………………………………………………10mg
URTIRIZINE SYRUP 5MG/5ML
Each 5ml contains:
Cetirizine
diHCL…………………………………………………5mg
PRODUCT DESCRIPTION:
URTIRIZINE TABLETS 10MG
A white, scored, oblong tablet of size 10 x 4mm.
URTIRIZINE SYRUP 5MG/5ML
A colorless, liquid with pineapple flavor and sweet taste.
PHARMACODYNAMICS
Cetirizine hydrochloride, a human metabolite of hydroxyzine, is a
potent antihistamine that selectively inhibits the effect of
peripheral H (1)-receptors.
Cetirizine belongs to the piperazine class of antihistamines and is
the major carboxylated metabolite of hydroxyzine. However,
it is less lipophilic than hydroxyzine and thus less likely to
distribute into the central nervous system (CNS) and produce
sedation.
Generally, antihistamines contain 1 or 2 heterocyclic or aromatic
rings attached to the side chain of histamine. Cetirizine has
more polar or less lipophilic functional groups attached to the
ethylamine side chain which has resulted in less CNS
penetration, greater selectivity for the H1-receptor, and less
anticholinergic side effects. Cetirizine may also have a modulatory
effect on inflammatory cells by inhibiting eosinophil migration or
eosinophilotactic mediators. Additionally, cetirizine may
also have inhibitory effects on other infiltrating inflammatory cells,
such as neutrophils.
Cetirizine has shown to be safe for allergic patients with mild to
moderate asthma and does not cause prolongation of QT
interval.
PHARMACOKINETICS:_ _
_Absorption _
Cetirizine is rapidly absorbed from the gastrointestinal tract after
oral doses and peak plasma concentrations occur within
about an hour.
Food delays the time to peak plasma concentrations but does not
decrease the amount of drug absorbed.
Bioavailability, oral : 70%.
The extent of bioavailability is similar when cetirizine is given a