Land: Maleisië
Taal: Engels
Bron: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
NEOMYCIN SULPHATE
HOVID BERHAD
NEOMYCIN SULPHATE
15 gm
HOVID BERHAD
HOVID NEOMYCIN CREAM 0.5% VINEO01-VAR2 (MY) 100 DESCRIPTION White, opaque cream. COMPOSITION Neomycin Sulphate 0.5% w/w PHARMACODYNAMICS AND PHARMACOKINETICS Neomycin, a bactericidal antibiotic, is actively transported across the bacterial cell membrane, binds to 30S subunit of bacterial ribosomes, and interferes with an initiation complex between messenger RNA and the 30S subunit, thus inhibiting protein synthesis. Neomycin is not absorbed percutaneously, but is readily absorbed from large denuded, burned or granulating areas. INDICATIONS For treatment of infections of the skin due to susceptible staphylococci and other neomycin-sensitive organisms. CONTRAINDICATIONS • Avoid in patients known to be hypersensitive to aminoglycosides. • Prolonged use is not recommended as it may lead to skin sensitisation. • Do not use on deep or punctured wounds, serious burns, or raw areas unless directed by physician. • Concurrent topical and systemic administration of neomycin or related drugs is not recommended since hypersensitivity reactions may occur more frequently under these circumstances. • This medication is not for ophthalmic use. PRECAUTIONS Caution in patients with extensive skin damage or perforated tympanic membranes as deafness may result. PREGNANCY AND LACTATION Safety for use in pregnancy and lactation has not been established. DRUG INTERACTIONS Concurrent topical use of other aminoglycosides with neomycin or related drugs is not recommended since hypersensitivity reactions may occur more frequently. MAIN SIDE/ADVERSE EFFECTS Hypersensitivity reactions, usually of the delayed type. DOSAGE AND ADMINISTRATION Route of administration: Topical Adults and Children: Apply to the affected area one to three times a day. Note: The treated area(s) may be covered with a gauze dressing if desired. Storage: Store below 30 ˚ C. Protect from freezing. Presentation/Packing: Cream 0.5% x 15 g, 30 g (Not all presentations may be available locally) Product Registration Holder / Manufactured by: HOVID Bhd. 121, Jalan T Lees het volledige document