"英特萊"錠200毫克

Country: Tajwan

Lingwa: Ċiniż

Sors: 衛生福利部食品藥物管理署 (Ministry of Health and Welfare, Food And Drug Administration)

Ingredjent attiv:

ETRAVIRINE

Disponibbli minn:

嬌生股份有限公司 台北市中山區民生東路三段2號10樓及11樓 (30814854)

Kodiċi ATC:

J05AG04

Għamla farmaċewtika:

錠劑

Kompożizzjoni:

主成分 (Formulation of Drug Product:) ; ETRAVIRINE (0818004000) MG

Unitajiet fil-pakkett:

塑膠瓶裝

Klassi:

製　劑

Tip ta 'preskrizzjoni:

須由醫師處方使用

Manifatturat minn:

JANSSEN-CILAG SPA VIA C. JANSSEN, B.GO SAN MICHELE, 04100 LATINA, ITALY IT

Żona terapewtika:

etravirine

Indikazzjonijiet terapewtiċi:

INTELENCE與抗反轉錄病毒藥物併用，適用於曾有抗病毒藥物治療經驗，對過去的治療無效，且對NNRTI及其他抗反轉錄病毒藥物產生抗藥性之愛滋病毒HIV-1感染之成人患者。

Sommarju tal-prodott:

有效日期: 2023/06/27; 英文品名: Intelence Tablets 200mg

Data ta 'l-awtorizzazzjoni:

2013-06-27

Fuljett ta 'informazzjoni

200
INTELENCE TABLETS 200 MG
025918
1.
INTELENCE T
ablets 200 mg
200
2.
200 mg
Etravirine
6.1
3.
200
4.
4.1
INTELENCE
NNRTI
HIV-1
4.2
INTELENCE
INTELENCE
200 mg
100 mg
5.2
INTELENCE
INTELENCE
5.2
INTELENCE
5.2
Child-Pugh
A
B
INTELENCE
INTELENCE
Child-Pugh
C
INTELENCE
4.4
5.2
5.2
4.3
Etravirine
4.4
HIV
INTELENCE
HIV
INTELENCE
5.1
3
V90I
A98G
L100I
K101E / P
V106I
V179D / F
Y181C/ I / V
G190A / S
INTELENCE
5.1
Etravi
ne
raltegravir
maraviroc
4.5
1
2
4.8
INTELENCE
Stevens-Johnson Syndrome
< 0.1%
INTELENCE
NNRTI
INTELENCE
INTELENCE
DUET
INTELENCE
INTELENCE
DRESS
TEN
4.8
DRESS
3-6
INTELENCE
INTELENCE
INTELENCE
65
53
56
64
INTELENCE
55
4.2
5.2
Etravirine
INTELENCE
Child-
Pugh
C
4.2
5.2
B
C
B
C
CART
HIV
visceral lipomatosis
酶
PIs
lipoatrophy
NRTIs
4.8
HIV
CART
CART
Pneumocystis
jiroveci
4.8
HIV
INTELENCE
tipranavir
ritonavir
Etravirine
76%
INTELENCE
4.5
4.5
Etravirine
Etravirine
CYP3A4
CYP2C9
CYP2C19
苷
酶
UDPGT
glucuronidation
CYP
3A4
CYP2C9
CYP2C19
Etravirine
Etravirine
INTELENCE
CYP3A4
CYP2C9
CYP2C19
Etravirine
Etravirine
Etravirine
Etravirine
CYP3A4
INTELENCE
CYP3A4
Etravirine
CYP2C9
CYP2C19
P-glycoprotein
INTELENCE
CYP2C9
CYP2C19
P-glycoprotein
Etravirine
↑
↓
↔
ND
q.d.
q.a.m.
b.i.d.
CI
Etravirine
90% CI
1.00=
苷
苷
酶
NR
TIs
Didanosine
400 mg q.d.
Didanosine AUC
↔
0.99
0.79-1.25
Didanosine C
min
ND
Didanosine C
max
↔
0.91
0.58-1.42
Etravirine AUC
↔
1.11
0.99-1.25
Etravirine C
min
↔
1.05
0.93-1.18
Etravirine C
max
↔
1.16
1.02-1.32
Didanosine
Etravirine
INTELENCE
didanosine
Tenofovir 300 mg
q.d.
Tenofovir AUC
↔
1.15
1.09-1.21
Tenofovir C
min
↑
1.19
1.13-1.26
Tenofovir C
max
↑
1.15
1.04-1.27
Etravirine AUC
↓
0.81
0.75-0.88
Etravirine C
min
↓
0.82
0.73-0.91
Etravirine C
max
↓
0.81
0.75-0.88
Tenofovir
Etravirine
INTELENCE
tenofovir
NRTIs
NRTIs
abacaviremtricitabine
lamivudinestavudinezidovudine
INTELENCE
INTELENCE
NRTIs
苷
酶
NNR
TIs
Efavirenz
Nevirapine
NNRTIs
INTELENCE
Efavirenz
Nevirapine
Etravirine
INTELENCE
INTELENCE
NNRTIs
酶
PIs
ritonavir
Nelfinavir
INTELENCE
Nelfinavir
INTEL